4 completed, 1 unknown. 3 Phase 1, 1 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Completed 3 |
| Phase 2 | 1 | Completed 1 |
| Phase 3 | 1 | Unknown 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of Efficacy and Safety of PHP-201 in Patients With Primary Open Angle Glaucoma or Ocular Hypertension Placebo ophthalmic solution, PHP-201 ophthalmic solution - Primary Open Angle Glaucoma, Ocular Hypertension | Phase 3 | Unknown | pH Pharma | 110 | 2021-11-01 | 2021-06-18 |
| A Study of Safety, Tolerability, and Pharmacokinetics of Multiple-Ascending Doses of PHP-303 in Otherwise Healthy Overweight or Obese Subjects PHP-303, Placebo - Otherwise Healthy Overweight or Obese | Phase 1 | Completed | pH Pharma | 50 | 2018-12-17 | 2020-04-13 |
| A Study of Safety, Tolerability, and Pharmacokinetics of Single Doses of PHP-303 in Healthy Subjects PHP-303, Placebo - Healthy Volunteer | Phase 1 | Completed | pH Pharma | 49 | 2018-08-02 | 2020-04-13 |
| PK/PD, Safety and Tolerability of PHP-201 Topical Eye Drop in Korean and Japanese Healthy Subjects PHP-201 0.5% ophthalmic solution (topical eye drop) - Healthy Volunteer | Phase 1 | Completed | pH Pharma | 24 | 2018-02-04 | 2018-07-16 |
| Evaluation of PHP-201 Ophthalmic Solution in Patients With Normal Tension Glaucoma PHP-201 0.25% ophthalmic solution, PHP-201 0.5% ophthalmic solution, Placebo ophthalmic solution - Normal Tension Glaucoma | Phase 2 | Completed | pH Pharma | 119 | 2017-03-06 | 2018-10-26 |
Glaucoma (1) · Glaucoma, Open-Angle (1) · Low Tension Glaucoma (1) · Obesity (1) · Ocular Hypertension (1)
sovesudil (3) · Ophthalmic Solutions (2)
South Korea (3) · United States (2)
Andrew Nicholls, MD, PhD (1) · Brian Roberts, MD (1) · Soojin Kim (1) · Younyoung Hwang (1)