5 completed. 4 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Completed 4 |
| Phase 1 | 1 | Completed 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase II Study to Evaluate the Effectiveness of EVT 302 in Smoking Cessation. EVT 302, Placebo, EVT 302 plus open label Nicotine replacement - Smoking Cessation | Phase 2 | Completed | Evotec Neurosciences GmbH | 400 | 2008-08-01 | 2009-05-29 |
| Effects of EVT 302 With or Without NRT on Craving and Withdrawal in Healthy Male Smokers Deprived of Cigarettes EVT 302, 10 mg, placebo, Nicotine replacement therapy (NRT) - Smoking Cessation | Phase 2 | Completed | Evotec Neurosciences GmbH | 90 | 2008-02-01 | 2008-06-17 |
| The Effects of a Novel NMDA NR2B-Subtype Selective Antagonist, EVT 101, on Brain Function EVT 101, placebo - Human Volunteers | Phase 1 | Completed | Evotec Neurosciences GmbH | 19 | 2007-09-01 | 2008-02-18 |
| Efficacy Study of EVT 201 in the Treatment of Elderly Patients With Daytime Sleepiness EVT 201 - Sleep Initiation and Maintenance Disorders | Phase 2 | Completed | Evotec Neurosciences GmbH | 135 | 2006-11-01 | 2008-01-07 |
| Efficacy Study of EVT 201 to Treat Insomnia EVT 201 - Sleep Initiation and Maintenance Disorders | Phase 2 | Completed | Evotec Neurosciences GmbH | 66 | 2006-09-01 | 2008-01-30 |
Sleep Initiation and Maintenance Disorders (2) · Smoking Cessation (2)
EVT 201 (2) · sembragiline (2) · Nicotine Replacement Therapy (1)
Germany (2) · United States (2) · United Kingdom (1)
James K Walsh, PhD (2) · Alla Radicke, MD (1) · H D Stahl, MD, PhD (1) · Nigel Leigh, BSc MBBS Phd (1)