3 completed, 1 terminated. 4 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Completed 3, Terminated 1 |
| Phase 2 | 1 | Completed 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Eryaspase With Modified FOLFIRINOX in Advanced Pancreatic Ductal Adenocarcinoma Eryaspase, FOLFIRINOX - Locally Advanced Pancreatic Ductal Adenocarcinoma, Metastatic Pancreatic Ductal Adenocarcinoma | Phase 1 | Completed | Georgetown University | 19 | 2020-12-02 | 2025-06-11 |
| L-asparaginase Encapsulated in Red Blood Cells (Eryaspase) for Treatment of Adult Patients With ALL or LBL L-asparaginase encapsulated in RBC - Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma | Phase 1 | Terminated | ERYtech Pharma | 14 | 2013-10-01 | 2018-07-05 |
| Administration of GRASPA (Suspension of Erythrocytes Encapsulating L-asparaginase)in Patients With Pancreatic Cancer GRASPA - Pancreatic Cancer | Phase 1 | Completed | ERYtech Pharma | 12 | 2009-11-01 | 2021-10-15 |
| Administration of Allogenic Red Blood Cells Loaded L-asparaginase in Cases of Relapse of Acute Lymphoblastic Leukaemia GRASPA, native L asparaginase - Acute Lymphoblastic Leukemia | Phase 1 / Phase 2 | Completed | ERYtech Pharma | 25 | 2006-01-01 | 2012-01-11 |
Precursor Cell Lymphoblastic Leukemia-Lymphoma (2) · Leukemia (1) · Lymphoma (1) · Pancreatic Neoplasms (1) · Recurrence (1)
eryaspase (2) · Erythrocyte Count (1) · Fluorouracil (1) · Irinotecan (1) · Leucovorin (1) · Oxaliplatin (1) · folfirinox (1)
United States (2) · France (1)
Marcus S Noel, MD (1) · Yves Bertrand, MD PhD (1)