4 completed, 1 active not recruiting. 4 Phase 4, 1 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 4 | Completed 3, Active not recruiting 1 |
| Early Phase 1 | 1 | Completed 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Smoking Cessation and Functional CT Assessment Sildenafil 20 MG, Placebo Oral Tablet, Pulse wave velocity - Emphysema | Phase 4 | Completed | Eric A. Hoffman | 162 | 2018-03-19 | 2025-02-14 |
| Functional CT Assessment of Pulmonary Arterial Dysfunction in Smoking Associated Emphysema Sildenafil - Emphysema | Phase 4 | Active not recruiting | Eric A. Hoffman | 17 | 2017-07-10 | 2025-04-15 |
| Hypoxic Pulmonary Vasoconstriction Pilot Study Sildenafil study group - Emphysema | Phase 4 | Completed | Eric A. Hoffman | 22 | 2011-06-29 | 2019-10-01 |
| Repeatability in Hyperpolarized 3-Helium With MRI Prone hyperpolarized 3 helium gas scan, Supine hyperpolarized 3 helium gas scan, Vitals - Radiation Exposure | Phase 4 | Completed | Eric A. Hoffman | 18 | 2008-07-22 | 2023-11-01 |
| Image and Model Based Analysis of Lung Disease Pulmonary Function Test, CT Scans, Questionnaires - Pulmonary Disease, Chronic Obstructive | Early Phase 1 | Completed | Eric A. Hoffman | 341 | 1997-09-30 | 2019-01-22 |
Emphysema (3) · Pulmonary Disease, Chronic Obstructive (1)
Sildenafil Citrate (3) · Respiratory Function Tests (2) · Contrast Media (1) · Lasers, Gas (1) · Pulse Wave Analysis (1) · Surveys and Questionnaires (1) · Tomography, X-Ray Computed (1)
United States (5)
Eric A Hoffman, PhD (3) · Eric A Hoffman (1) · Eric Hoffman, PhD (1)
R01HL130883 (2), R01HL064368 (1), R01HL112986 (1)