4 completed, 4 terminated, 1 recruiting. 6 Phase 1, 5 Phase 2, 2 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 6 | Completed 3, Terminated 2, Recruiting 1 |
| Phase 2 | 5 | Terminated 3, Completed 1, Recruiting 1 |
| Not applicable | 2 | Completed 1, Terminated 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| EO4010 in Previously Treated Metastatic Colorectal Carcinoma EO4010 - Colorectal Cancer Metastatic | Phase 1 / Phase 2 | Terminated | Enterome | 25 | 2023-06-01 | 2026-10-19 |
| EO2040 in Combination With Nivolumab, for Treatment of Patients With Minimal Residual Disease of Colorectal Cancer EO2040 - Colorectal Cancer | Phase 2 | Terminated | Enterome | 1 | 2023-03-01 | 2025-09-29 |
| A Novel Vaccine (EO2463) as Monotherapy and in Combination, for Treatment of Patients With Indolent Non-Hodgkin Lymphoma EO2463, lenalidomide, rituximab - Follicular Lymphoma, Marginal Zone Lymphoma | Phase 1 / Phase 2 | Recruiting | Enterome | 80 | 2021-07-05 | 2026-01-30 |
| A Novel Therapeutic Vaccine (EO2401) in Metastatic Adrenocortical Carcinoma, or Malignant Pheochromocytoma/Paraganglioma EO2401, Nivolumab - Adrenocortical Carcinoma, Pheochromocytoma | Phase 1 / Phase 2 | Terminated | Enterome | 70 | 2020-07-23 | 2026-01-30 |
| First-in-Human, Phase 1b/2a Trial of a Multipeptide Therapeutic Vaccine in Patients With Progressive Glioblastoma Multiple dose of EO2401 - Glioblastoma, Adult | Phase 1 / Phase 2 | Completed | Enterome | 100 | 2020-07-13 | 2025-11-28 |
| A Study of a FimH Blocker, EB8018, in Crohn's Disease Patients EB8018 (First-in-class FimH blocker) - Crohn Disease | Phase 1 | Completed | Enterome | 8 | 2018-03-07 | 2021-02-02 |
| Characteristics of the Intestinal Microbiota in Patients With Cancer Collection of stool and serum samples - Oncology | Not applicable | Completed | Centre Georges Francois Leclerc | 69 | 2017-02-06 | 2020-01-27 |
| First-in-Human Single and Multiple Dose of EB8018 Single Ascending Doses of EB8018, Single Ascending Doses of placebo, Multiple Ascending Doses of EB8018 - Healthy Volunteers | Phase 1 | Completed | Enterome | 60 | 2016-11-01 | 2018-02-13 |
| MOlecular BIomarkers and Adherent and Invasive Escherichia Coli (AIEC) Detection Study In Crohn's Disease Patients Biopsies, stool and blood collection - Crohn's Disease | Not applicable | Terminated | Enterome | 143 | 2016-09-01 | 2018-06-12 |
Crohn Disease (2) · Adrenocortical Carcinoma (1) · Colorectal Neoplasms (1) · Glioblastoma (1) · Lymphoma, B-Cell, Marginal Zone (1) · Lymphoma, Follicular (1) · Neoplasms (1) · Paraganglioma (1) · Pheochromocytoma (1)
Nivolumab (3) · Bevacizumab (1) · Biopsy (1) · Defecation (1) · Lenalidomide (1) · Rituximab (1)
France (7) · United States (6) · Spain (4) · Germany (3) · Italy (3) · United Kingdom (2) · Austria (1) · Denmark (1) · Netherlands (1) · Sweden (1)
Jan Fagerberg, MD (2) · Jean-Michel Paillarse (2) · Jan Fagerberg (1)