7 terminated. 7 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 7 | Terminated 7 |
| Phase 2 | 2 | Terminated 2 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Avelumab In Combination Regimens That Include An Immune Agonist, Epigenetic Modulator, CD20 Antagonist and/or Conventional Chemotherapy in Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma (R/R DLBCL) Avelumab, Utomilumab, Rituximab - Diffuse Large B-Cell Lymphoma | Phase 3 | Terminated | Pfizer | 29 | 2016-12-16 | 2020-12-17 |
| Tecemotide Following Concurrent Chemo-radiotherapy for Non-small Cell Lung Cancer Tecemotide, Placebo, Cyclophosphamide (CPA) - Carcinoma, Non-Small-Cell Lung | Phase 3 | Terminated | EMD Serono | 35 | 2014-03-01 | 2017-08-23 |
| Growth Hormone in Poor Responders to IVF Trial Saizen (Human Growth Hormone), No Saizen Control (Standard IVF Protocol) - Infertility | Phase 2 / Phase 3 | Terminated | Pacific Centre for Reproductive Medicine | 60 | 2012-06-01 | 2014-07-23 |
| Saizen® Solution for Injection Adult Growth Hormone Deficiency (GHD) Immunogenicity Study Saizen® - Growth Hormone Deficiency (GHD) | Phase 3 | Terminated | EMD Serono | 59 | 2010-10-01 | 2013-08-07 |
| STRIDE - STimulating Immune Response In aDvanced brEast Cancer Tecemotide (L-BLP25) and Hormonal Treatment, Placebo of tecemotide (L-BLP25) and Hormonal Treatment, cyclophosphamide - Breast Cancer | Phase 3 | Terminated | EMD Serono | 16 | 2009-09-01 | 2014-07-24 |
| The Efficacy and Safety of Atacicept in Combination With Mycophenolate Mofetil Used to Treat Lupus Nephritis Atacicept, Mycophenolate mofetil, Placebo - Lupus Nephritis | Phase 2 / Phase 3 | Terminated | EMD Serono | 6 | 2007-12-01 | 2016-03-23 |
| Onercept in the Treatment and Re-Treatment of Subjects With Moderate to Severe Plaque Psoriasis Onercept, Placebo - Arthritis, Psoriatic | Phase 3 | Terminated | EMD Serono | 854 | 2004-09-01 | 2013-10-22 |
Arthritis, Psoriatic (1) · Breast Neoplasms (1) · Carcinoma, Non-Small-Cell Lung (1) · Dwarfism, Pituitary (1) · Infertility (1) · Lupus Nephritis (1) · Lymphoma, Large B-Cell, Diffuse (1) · Nephritis (1) · Recurrence (1)
Cyclophosphamide (2) · Human Growth Hormone (2) · L-BLP25 (2) · Sodium Chloride (2) · Adrenal Cortex Hormones (1) · Azacitidine (1) · Bendamustine Hydrochloride (1) · Gemcitabine (1) · Mycophenolic Acid (1) · Oxaliplatin (1) · Rituximab (1) · TACI receptor-IgG Fc fragment fusion protein (1) · avelumab (1) · recombinant human tumor necrosis factor-binding protein-1 (1) · utomilumab (1)
United States (6) · Australia (2) · Belgium (2) · Canada (2) · Czechia (2) · Germany (2) · Poland (2) · South Korea (2) · Austria (1) · Israel (1) · Italy (1) · Malaysia (1) · Russia (1) · Singapore (1) · Slovakia (1)
Oscar Kashala, MD, PhD, DSc (1)
PMID 20718590, PMID 22325903, PMID 34687398, PMID 40443562
2008 (1), 2016 (1)