7 completed. 7 Phase 1.
By phase and status
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Trials (filtered) newest first · largest first
All 7 trials
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|
A Trial to Evaluate the Effect of Itraconazole (ITZ), a CYP3A4 Inhibitor, on the Pharmacokinetics of the Soluble Guanylate Cyclase Stimulator, Olinciguat (IW-1701), in Healthy Volunteers
Olinciguat, Itraconazole - Healthy | Phase 1 | Completed | 24 | 2019-05-03 | 2019-07-15 |
A Trial to Study the Absorption, Metabolism, and Excretion of [14C]-Praliciguat in Healthy Male Volunteers
[14C]-praliciguat - Healthy Volunteers | Phase 1 | Completed | 8 | 2019-03-01 | 2019-06-19 |
A Trial to Study the Absorption, Metabolism, and Excretion of [14C]-Olinciguat in Healthy Male Volunteers
[14C]-olinciguat - Healthy Volunteers | Phase 1 | Completed | 8 | 2019-01-17 | 2019-04-03 |
A Trial to Evaluate the Effect of Itraconazole (ITZ), a CYP3A4 Inhibitor, on the Pharmacokinetics of Praliciguat (IW-1973) in Healthy Volunteers
IW-1973, Itraconazole - Healthy | Phase 1 | Completed | 24 | 2018-04-12 | 2019-04-03 |
A Trial of IW-1701, A Stimulator of Soluble Guanylate Cyclase (sGC), in Healthy Subjects
IW-1701, Placebo - Healthy | Phase 1 | Completed | 67 | 2016-05-01 | 2019-04-03 |
Trial of IW-1973 (A Stimulator of Soluble Guanylate Cyclase (sGC)) in Healthy Volunteers
IW-1973, Matching Placebo Tablet - Healthy | Phase 1 | Completed | 54 | 2015-11-01 | 2019-04-03 |
Trial of IW-1701 (A Stimulator of Soluble Guanylate Cyclase (sGC)) in Healthy Volunteers
IW-1701, Matching Placebo - Healthy | Phase 1 | Completed | 24 | 2015-10-01 | 2019-04-03 |
Interventions
Itraconazole (2) · praliciguat (2)
Countries
United States (7)
Top investigators
Bina Tejura, MD (2) · John Hanrahan, MD (2)