2 completed, 1 active not recruiting. 3 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Completed 2, Active not recruiting 1 |
| Phase 2 | 2 | Active not recruiting 1, Completed 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase I/IIa Study of Concomitant Radiotherapy With Olaparib and Temozolomide in Unresectable High Grade Gliomas Patients Olaparib, Temozolomide (TMZ), IMRT (Intensity Modulated Radiation Therapy) - Malignant Gliomas, Radiotherapy | Phase 1 / Phase 2 | Active not recruiting | Centre Francois Baclesse | 91 | 2017-09-04 | 2025-12-04 |
| Intrathecal Trastuzumab Administration in Metastatic Breast Cancer Patients Developing Carcinomatous Meningitis Trastuzumab - Metastatic Breast Cancer, Carcinomatous Meningitis | Phase 1 / Phase 2 | Completed | Institut Curie | 34 | 2011-05-19 | 2025-11-24 |
| Safety Evaluation of a Combination of Brain Radiation Therapy and Bevacizumab (AvastinĀ®) for Treatment of Brain Metastasis Bevacizumab - Metastatic Malignant Neoplasm to Brain | Phase 1 | Completed | Centre Francois Baclesse | 21 | 2010-06-01 | 2013-09-12 |
Brain Neoplasms (1) · Breast Neoplasms (1) · Glioma (1) · Meningeal Carcinomatosis (1)
Bevacizumab (1) · Radiotherapy, Intensity-Modulated (1) · Temozolomide (1) · Trastuzumab (1) · olaparib (1)
France (3)
PMID 25274615, PMID 29635147, PMID 35344040, PMID 39882966
2009 (1)