6 completed, 2 terminated, 2 unknown. 10 Phase 1, 8 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 10 | Completed 6, Terminated 2, Unknown 2 |
| Phase 2 | 8 | Completed 6, Terminated 1, Unknown 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| GVAX in Advanced Prostate Cancer Patients Made Lymphopenic GM-CSF gene transduced allogeneic vaccine GVAX - Prostate Cancer | Phase 1 / Phase 2 | Unknown | Providence Health & Services | 18 | 2005-07-01 | 2009-02-24 |
| Dose-Escalation Study of CG0070 for Bladder Cancer After BCG (Bacillus Calmette-Guerin) Failure Oncolytic adenovirus (serotype 5) - CG0070 - Carcinoma, Transitional Cell, Bladder Neoplasms | Phase 1 | Unknown | Cell Genesys | 75 | 2005-04-01 | 2008-10-03 |
| Phase 1 Trial of Ipilimumab and GVAX in Patients With Metastatic Castration-resistant Prostate Cancer GVAX and ipilimumab - Prostate Cancer | Phase 1 | Terminated | Amsterdam UMC, location VUmc | 28 | 2004-11-01 | 2012-01-16 |
| Intravenous CG7870 in Combination With Docetaxel in Patients With Metastatic Hormone-Refractory Prostate Cancer CG7870 - Prostate Cancer | Phase 1 / Phase 2 | Terminated | Cell Genesys | 69 | 2004-08-01 | 2006-02-02 |
| Dose Escalation and Efficacy Trial of GVAX® Prostate Cancer Vaccine Immunotherapy allogeneic GM-CSF secreting cellular vaccine - Prostate Cancer | Phase 1 / Phase 2 | Completed | Cell Genesys | 80 | 2001-12-01 | 2007-12-24 |
| Vaccination in the Peripheral Stem Cell Transplant Setting for Multiple Myeloma Therapeutic Cellular Vaccine, GM-CSF Producing - Multiple Myeloma | Phase 1 / Phase 2 | Completed | Cell Genesys | 22 | 2000-10-01 | 2007-12-24 |
| Prime-Boost Dose Scheduling Trial for Human GM-CSF Gene Transduced Irradiated Prostate Allogeneic Cancer Cell Vaccines (Allogeneic Prostate GVAX®) Immunotherapy allogeneic GM-CSF secreting cellular vaccine - Prostate Cancer | Phase 1 / Phase 2 | Completed | Cell Genesys | 20 | 1999-05-01 | 2005-09-01 |
| Prime-Boost Dose Scheduling Trial for Human GM-CSF Gene Transduced Irradiated Prostate Allogeneic Cancer Vaccine (Allogeneic Prostate GVAX®) in Patients With Hormone-Refractory Prostate Cancer Immunotherapy allogeneic GM-CSF secreting cellular vaccine - Prostate Cancer | Phase 1 / Phase 2 | Completed | Cell Genesys | 50 | 1999-05-01 | 2005-09-01 |
| Vaccination Priming and Vaccine Boosting Trial of Allogeneic Human GM-CSF Gene Transduced Irradiated Prostate Cancer Cell Vaccines (GVAX® Vaccine for Prostate Cancer) Immunotherapy allogeneic GM-CSF secreting cellular vaccine - Prostate Cancer | Phase 1 / Phase 2 | Completed | Cell Genesys | 36 | 1998-12-01 | 2005-09-01 |
| Trial of IV Injection of CV787 in Hormone Refractory Metastatic Prostate Cancer CV787 (CG7870) - Prostate Cancer | Phase 1 / Phase 2 | Completed | Cell Genesys | 2005-06-28 |
Prostatic Neoplasms (8) · Neoplasms (7) · Neoplasm Metastasis (5) · Adenoviridae Infections (1) · Carcinoma in Situ (1) · Carcinoma, Transitional Cell (1) · Multiple Myeloma (1) · Non-Muscle Invasive Bladder Neoplasms (1) · Urinary Bladder Neoplasms (1)
Ipilimumab (1)
United States (5) · Canada (1) · Netherlands (1)
Bernard Fox, PhD (1) · Fons van den Eertwegh, MD PhD (1) · Winald Gerritsen, Prof. MD PhD (1)