7 completed, 1 not yet recruiting, 1 withdrawn. .
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Saphnelo Use in Females of Child-bearing Potential Anifrolumab - Systemic Lupus Erythematosus | Not yet recruiting | AstraZeneca | 26000000 | 2026-10-01 | 2026-02-25 | |
| Emulation of the KEYNOTE-189 Trial Using Electronic Health Records Pembrolizumab + Pemetrexed-Platinum, Pemetrexed-Platinum - Non-small Cell Lung Cancer, Metastatic Lung Cancer | Completed | Aetion, Inc. | 1854 | 2023-06-05 | 2023-09-13 | |
| Post-marketing Safety of Elasomeran/Davesomeran and Andusomeran SPIKEVAX - SARS-CoV-2 | Completed | ModernaTX, Inc. | 15196685 | 2023-04-14 | 2024-12-19 | |
| A Non-interventional Multi-country Cohort Study to Assess the Safety of EVUSHELD™ During Pregnancy Pregnancy, Pregnant Women | Withdrawn | AstraZeneca | 2022-06-27 | 2023-12-22 | ||
| Methodologies for Observational Studies Comparing Inpatient COVID-19 Treatments Initiation of IL6Ri (tocilizumab or sarilumab) versus JAKi (baricitinib or tofacitinib) added to systemic corticosteroids of interest (CSI) - COVID-19 | Completed | Aetion, Inc. | 1442 | 2020-06-16 | 2024-09-19 | |
| Dexamethasone and COVID-19 Inpatient Mortality Dexamethasone Oral - Coronavirus | Completed | Aetion, Inc. | 14105 | 2020-04-01 | 2023-04-18 | |
| CARE Initiative: Real-world Emulation of the KEYNOTE-189 Trial [DS4] Pembrolizumab, Pemetrexed, Cisplatin - Metastatic Non Small Cell Lung Cancer | Completed | Aetion, Inc. | 304 | 2010-02-01 | 2024-09-05 | |
| CARE Initiative: Real-world Emulation of the KEYNOTE-189 Trial [DS3] Pembrolizumab, Pemetrexed, Cisplatin - Metastatic Nonsmall Cell Lung Cancer | Completed | Aetion, Inc. | 851 | 2010-02-01 | 2024-09-23 | |
| CARE Initiative: Real-world Emulation of the PALOMA-2 Trial Palbociclib, Letrozole - Metastatic Breast Cancer | Completed | Aetion, Inc. | 724 | 2010-02-01 | 2024-09-23 |
Neoplasms (4) · Carcinoma, Non-Small-Cell Lung (3) · COVID-19 (2) · Coronavirus Infections (2) · Breast Neoplasms (1) · Lung Neoplasms (1) · Lupus Erythematosus, Systemic (1) · Virus Diseases (1)
pembrolizumab (3) · Carboplatin (2) · Cisplatin (2) · Pemetrexed (2) · 2019-nCoV Vaccine mRNA-1273 (1) · CVnCoV COVID-19 vaccine (1) · Dexamethasone (1) · Letrozole (1) · anifrolumab (1) · baricitinib (1) · palbociclib (1) · sarilumab (1) · tocilizumab (1) · tofacitinib (1)
United States (4)
David Merola, PharmD, PhD (1) · Liz M Garry, PhD (1) · Vera Frajzyngier, PhD (1) · Zachary Bouck (1)