5 recruiting, 2 not yet recruiting. 5 Phase 3, 2 Phase 1.
By phase and status
Follow Zenagamtide: new trials by email Literature Review of Zenagamtide trials Research Report on Zenagamtide
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
AMAZE 13: A Research Study Investigating How Well the Medicine Zenagamtide Helps People in Asia With Excess Body Weight Lose Weight Zenagamtide, Placebo ( matched to Zenagamtide) - Obesity, Overweight | Phase 3 | Not yet recruiting | 400 | 2027-01-07 | 2026-08-24 |
A Research Study to Look at How Well Zenagamtide Works Compared to Placebo in People With Established Atherosclerotic Cardiovascular Disease and Either Overweight or Obesity Zenagamtide, Placebo - Cardiovascular Risk, Obesity | Phase 3 | Not yet recruiting | 8500 | 2026-10-26 | 2026-10-06 |
A Research Study Investigating How Adults With Overweight or Obesity, With or Without Type 2 Diabetes, Tolerate Switching to a New Treatment (Zenagamtide) From Their Current Tirzepatide Medication Tirzepatide, Zenagamtide - Overweight, Obesity | Phase 1 | Recruiting | 60 | 2026-10-08 | 2026-10-16 |
A Research Study Investigating How Adults With Overweight or Obesity, With or Without Type 2 Diabetes, Tolerate Switching to a New Treatment (Zenagamtide) From Their Current Semaglutide Medication Semaglutide, Zenagamtide - Overweight, Obesity | Phase 1 | Recruiting | 60 | 2026-10-05 | 2026-10-16 |
A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide Zenagamtide, Semaglutide, Placebo (matched to semaglutide) - Overweight, Obesity | Phase 3 | Recruiting | 650 | 2026-09-22 | 2026-09-28 |
AMAZE 9: A Research Study Investigating How Well Zenagamtide Tablets Help People With Excess Body Weight Lose Weight zenagamtide, Placebo - Overweight, Obesity | Phase 3 | Recruiting | 950 | 2026-08-31 | 2026-09-28 |
AMBITION 7: A Research Study Investigating How Well Zenagamtide Lowers Blood Sugar and Body Weight Compared to Insulin Glargine in People With Type 2 Diabetes and Increased Risk of Diseases That Affect the Heart and Blood Vessels Treated With 1-3 Other Diabetes Medications Zenagamtide, Insulin glargine U-100 - Type 2 Diabetes, Cardiovascular Risk | Phase 3 | Recruiting | 1778 | 2026-08-24 | 2026-09-01 |
Conditions studied
Obesity (6) · Overweight (5) · Diabetes Mellitus, Type 2 (3)
Sponsors
Novo Nordisk A/S (7)
Countries
United States (6) · India (3) · Argentina (2) · Brazil (2) · Bulgaria (2) · Canada (2) · China (2) · Czechia (2) · Germany (2) · Greece (2) · Italy (2) · Japan (2) · Malaysia (2) · Mexico (2) · Poland (2)