7 completed. 7 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 7 | Completed 7 |
Follow Xiaflex: new trials by email Literature Review of Xiaflex trials Research Report on Xiaflex
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effectiveness of Splinting After Collagenase Injection Collagenase Clostridium Histolyticum 0.9 MG [Xiaflex], Xiaflex + Hand-Based Custom Orthosis - Dupuytren Contracture, Dupuytren's Disease | Phase 3 | Completed | Foundation for Orthopaedic Research and Education | 80 | 2021-07-12 | 2025-02-26 |
| An Open-label Study to Assess the Safety and Effectiveness of AA4500 in Combination With the ErecAid® Esteem® Manual Vacuum Therapy System in Treating Men With Peyronie's Disease AA4500, ErecAid® Esteem® Manual Vacuum Therapy System, Investigator Modeling - Peyronie's Disease | Phase 3 | Completed | Endo USA Inc., a Keenova Therapeutics Company | 30 | 2014-10-01 | 2017-11-08 |
| A Phase 3, Open-label Study of the Safety and Effectiveness of AA4500 Administered Twice Per Treatment Cycle for up to Four Treatment Cycles (2 x 4) in Men With Peyronie's Disease AA4500 - Peyronie's Disease | Phase 3 | Completed | Endo USA Inc., a Keenova Therapeutics Company | 189 | 2012-09-01 | 2017-10-05 |
| Administration of Two Injections for Multiple Dupuytren's Contractures AA4500 collagenase clostridium histolyticum - Dupuytren's Contracture | Phase 3 | Completed | Endo USA Inc., a Keenova Therapeutics Company | 60 | 2011-09-01 | 2017-10-05 |
| A Study of AA4500 in Men With Peyronie's Disease AA4500 - Peyronie's Disease | Phase 3 | Completed | Endo USA Inc., a Keenova Therapeutics Company | 348 | 2010-11-01 | 2017-10-05 |
| Study of AA4500 in the Treatment of Peyronie's Disease AA4500, Placebo - Peyronie's Disease | Phase 3 | Completed | Endo USA Inc., a Keenova Therapeutics Company | 418 | 2010-10-01 | 2017-10-05 |
| Study of AA4500 in the Treatment of Peyronie's Disease AA4500, Placebo - Peyronie's Disease | Phase 3 | Completed | Endo USA Inc., a Keenova Therapeutics Company | 418 | 2010-09-01 | 2017-10-05 |
Penile Induration (5) · Dupuytren Contracture (2)
Endo USA Inc., a Keenova Therapeutics Company (6) · Foundation for Orthopaedic Research and Education (1)
United States (5) · Australia (3) · United Kingdom (2) · Denmark (1) · France (1) · Germany (1) · Italy (1) · New Zealand (1) · Spain (1) · Sweden (1)
Gregory J. Kaufman, MD (2) · Gregory Kaufman, MD (2) · Jason Nydick, DO (1) · Neil Shusterman, MD (1) · Veronica Urdaneta, MD, MPPH (1)