8 completed, 1 withdrawn. 9 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 9 | Completed 8, Withdrawn 1 |
Follow Xiaflex: new trials by email Literature Review of Xiaflex trials Research Report on Xiaflex
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety and Effectiveness of EN3835 in the Treatment of EFP in Women Collagenase Clostridium Histolyticum - Edematous Fibrosclerotic Panniculopathy, Cellulite | Phase 2 | Completed | Endo USA Inc., a Keenova Therapeutics Company | 158 | 2017-11-17 | 2020-12-29 |
| EN3835 for the Treatment of Edematous Fibrosclerotic Panniculopathy (Commonly Known as Cellulite) Collagenase Clostridium Histolyticum - Edematous Fibrosclerotic Panniculopathy, Cellulite | Phase 2 | Completed | Endo USA Inc., a Keenova Therapeutics Company | 259 | 2016-10-05 | 2020-11-24 |
| EN3835 for the Treatment of Edematous Fibrosclerotic Panniculopathy (Commonly Known as Cellulite) COLLAGENASE CLOSTRIDIUM HISTOLYTICUM, Placebo Comparator - Edematous Fibrosclerotic Panniculopathy, Cellulite | Phase 2 | Completed | Endo USA Inc., a Keenova Therapeutics Company | 375 | 2016-02-01 | 2017-11-06 |
| Phase 2a Dose-Ranging Study to Evaluate Safety and Effectiveness of AA4500 in Treatment of Dupuytren's Disease Nodules Collagenase clostridium histolyticum, Placebo - Dupuytren's Disease | Phase 2 | Completed | Endo USA Inc., a Keenova Therapeutics Company | 76 | 2014-07-01 | 2017-10-05 |
| Clinical Study for the Treatment of Adhesive Capsulitis of the Shoulder Collagenase Clostridium Histolyticum, Placebo - Adhesive Capsulitis, Frozen Shoulder | Phase 2 | Completed | Endo USA Inc., a Keenova Therapeutics Company | 322 | 2013-11-01 | 2017-10-05 |
| A Phase 2, Randomized, Double-blind, Placebo Controlled Dose Ranging Study of Repeat Doses of AA4500 for the Treatment of Edematous Fibrosclerotic Panniculopathy Collagenase Clostridium Histolyticum, Placebo - Edematous Fibrosclerotic Panniculopathy (EFP) | Phase 2 | Completed | Endo USA Inc., a Keenova Therapeutics Company | 150 | 2013-10-01 | 2017-10-05 |
| A Dose Escalation Study Using Collagenase Clostridium Histolyticum in the Treatment of Lipoma Collagenase Clostridium Histolyticum - Lipoma | Phase 2 | Completed | Zachary Gerut | 14 | 2012-05-01 | 2016-10-06 |
| AA4500 for the Treatment of Adhesive Capsulitis of the Shoulder AA4500 0.29 mg/1 mL, AA4500 0.58 mg/2 mL, AA4500 0.58 mg/1 mL - Adhesive Capsulitis, Frozen Shoulder | Phase 2 | Completed | Endo USA Inc., a Keenova Therapeutics Company | 50 | 2011-11-01 | 2017-10-05 |
| Collagenase in the Treatment of Adhesive Capsulitis (Frozen Shoulder) Collagenase - Adhesive Capsulitis, Frozen Shoulder | Phase 2 | Withdrawn | Stony Brook University | 2006-01-01 | 2019-10-03 |
Cellulite (4) · Bursitis (3) · Dupuytren Contracture (1) · Lipoma (1) · Shoulder Pain (1)
Endo USA Inc., a Keenova Therapeutics Company (7) · Stony Brook University (1) · Zachary Gerut (1)
United States (9) · Australia (2)
Veronica Urdaneta, MD MPH (2) · Marie A Badalamente, PhD (1) · Mike McLane (1) · Mike McLane, PhD (1) · Neil H Schusterman, MD FACP (1) · Neil H Shusterman, MD FACP (1) · Zachary E Gerut, M.D. (1)