2 completed, 1 terminated, 1 withdrawn. 2 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 2 | Completed 1, Withdrawn 1 |
| Phase 2 | 2 | Completed 1, Terminated 1 |
Follow WEE1 Inhibitor AZD1775: new trials by email Literature Review of WEE1 Inhibitor AZD1775 trials Research Report on WEE1 Inhibitor AZD1775
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Wee1 Kinase Inhibitor AZD1775 and Combination Chemotherapy in Treating Children, Adolescents and Young Adults With Relapsed or Refractory Acute Myeloid Leukemia Cytarabine, Filgrastim, Fludarabine Phosphate - CNS 2a, CNS 2b | Phase 1 | Withdrawn | National Cancer Institute (NCI) | 2017-05-25 | 2017-05-03 | |
| WEE1 Inhibitor AZD1775 With or Without Cytarabine in Treating Patients With Advanced Acute Myeloid Leukemia or Myelodysplastic Syndrome Cytarabine, Laboratory Biomarker Analysis, Pharmacological Study - Chronic Myelomonocytic Leukemia, Myelodysplastic Syndrome With Isolated Del(5q) | Phase 2 | Completed | Mayo Clinic | 3 | 2017-05-05 | 2019-09-06 |
| WEE1 Inhibitor MK-1775, Docetaxel, and Cisplatin Before Surgery in Treating Patients With Borderline Resectable Stage III-IVB Squamous Cell Carcinoma of the Head and Neck Cisplatin, Docetaxel, Laboratory Biomarker Analysis - Head and Neck Squamous Cell Carcinoma | Phase 1 | Completed | University of Washington | 12 | 2015-07-22 | 2019-03-13 |
| Cisplatin With or Without WEE1 Inhibitor MK-1775 in Treating Patients With Recurrent or Metastatic Head and Neck Cancer Cisplatin, Laboratory Biomarker Analysis, Pharmacological Study - Recurrent Hypopharyngeal Squamous Cell Carcinoma, Recurrent Laryngeal Squamous Cell Carcinoma | Phase 2 | Terminated | National Cancer Institute (NCI) | 6 | 2014-03-01 | 2017-05-03 |
Leukemia, Myeloid, Acute (2) · Squamous Cell Carcinoma of Head and Neck (2) · Chromosome 5q Deletion Syndrome (1) · Leukemia, Myelomonocytic, Chronic (1) · Lymphoid Interstitial Pneumonia (1) · Myelodysplastic-Myeloproliferative Diseases (1) · Tongue Neoplasms (1)
National Cancer Institute (NCI) (2) · Mayo Clinic (1) · University of Washington (1)
United States (2) · Canada (1)
Eduardo Mendez (1) · Eric Winquist (1) · Maureen O'Brien (1) · Raoul Tibes (1)
N01CM00032 (1), P30CA015083 (1), P30CA015704 (1), UM1CA097452 (1)