6 recruiting, 2 active not recruiting, 1 completed, 1 not yet recruiting. 5 Phase 2, 3 Phase 3, 2 Phase 1, 1 Early Phase 1, 1 Not applicable.
Follow Volume Modulated Arc Therapy: new trials by email Literature Review of Volume Modulated Arc Therapy trials Research Report on Volume Modulated Arc Therapy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluating the Addition of Maintenance Immunotherapy Compared to the Usual Treatment of Chemotherapy and Autologous Stem Cell Transplant Alone for High-risk Patients With Relapsed or Refractory Hodgkin Lymphoma 3-Dimensional Conformal Radiation Therapy, Autologous Hematopoietic Stem Cell Transplantation, Biospecimen Collection - Recurrent Classic Hodgkin Lymphoma, Refractory Classic Hodgkin Lymphoma | Phase 2 / Phase 3 | Not yet recruiting | National Cancer Institute (NCI) | 374 | 2026-12-04 | 2026-07-08 |
| Consolidative Therapy After EV + Pembrolizumab in Muscle Invasive Bladder Cancer, REINFORCE Trial Intensity-Modulated Radiation Therapy, Volume Modulated Arc Therapy, Radiosensitizing Agent - Muscle Invasive Bladder Carcinoma, Stage III Bladder Cancer AJCC v8 | Phase 1 / Phase 2 | Recruiting | University of Washington | 12 | 2026-08-20 | 2026-08-25 |
| Testing Addition of an Anti-cancer Drug, Vorasidenib to Temozolomide, After Radiation for Advanced Brain Cancer Intensity-Modulated Radiation Therapy, Volume Modulated Arc Therapy, Pencil Beam Scanning - Astrocytoma, IDH-Mutant, Grade 3 | Phase 3 | Recruiting | Alliance for Clinical Trials in Oncology | 408 | 2026-06-24 | 2026-10-02 |
| Photon Craniospinal Irradiation for the Treatment of Leptomeningeal Disease Secondary to Breast Cancer or Non-small Cell Lung Cancer Biospecimen Collection, Craniospinal Irradiation, Electronic Health Record Review - Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Breast Carcinoma | Phase 2 | Recruiting | City of Hope Medical Center | 35 | 2025-05-05 | 2025-12-08 |
| Hippocampal Avoidance in Craniospinal Irradiation for the Treatment of Leptomeningeal Metastases From Breast Cancer or Non-small Cell Lung Cancer Biospecimen Collection, Computed Tomography, Electronic Health Record Review - Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Breast Carcinoma | Phase 2 | Recruiting | University of Washington | 22 | 2025-03-03 | 2026-08-14 |
| Personalized Ultrafractionated Stereotactic Adaptive Radiotherapy for Palliative Head and Neck Cancer Treatment (PULS-Pal) Personalized ultrafractionated stereotactic adaptive radiotherapy, Volume Modulated Arc Therapy, Computed Tomography - Head and Neck Carcinoma, Localized Head and Neck Carcinoma | Not applicable | Recruiting | Jonsson Comprehensive Cancer Center | 43 | 2024-10-25 | 2026-02-05 |
| Single Fraction or Multi-fraction Palliative Radiation Therapy for the Improvement of Quality of Life in Patients With Metastatic Gynecologic Cancers 3-Dimensional Conformal Radiation Therapy, Intensity-Modulated Radiation Therapy, Quality-of-Life Assessment - Metastatic Malignant Female Reproductive System Neoplasm | Phase 2 | Active not recruiting | M.D. Anderson Cancer Center | 28 | 2021-01-11 | 2026-09-18 |
| Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging 3-Dimensional Conformal Radiation Therapy, Apalutamide, Computed Tomography - Biochemically Recurrent Prostate Carcinoma, Metastatic Prostate Carcinoma | Phase 3 | Recruiting | ECOG-ACRIN Cancer Research Group | 804 | 2020-10-08 | 2026-08-19 |
| TBI Using IMRT (VMAT or Tomotherapy) for the Prevention of Pul Toxicities in Patients Undergoing Donor SCT Hematopoietic Cell Transplantation, Intensity-Modulated Radiation Therapy, Tomotherapy - Acute Leukemia, Myelodysplastic Syndrome | Phase 1 | Active not recruiting | City of Hope Medical Center | 20 | 2020-02-28 | 2026-08-05 |
| Nivolumab, Ipilimumab, and Radiation Therapy in Treating Patients With Stage III-IVB Head and Neck Cancer Nivolumab, Ipilimumab, Simultaneous-Integrated Boost Intensity-Modulated Radiation Therapy - Larynx, Lip, Oral Cavity and Pharynx | Early Phase 1 | Completed | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University | 24 | 2017-05-11 | 2025-04-29 |
Breast Neoplasms (2) · Carcinoma, Non-Small-Cell Lung (2) · Lung Neoplasms (2) · Meningeal Carcinomatosis (2) · Astrocytoma (1) · Laryngeal Diseases (1) · Lymphoid Interstitial Pneumonia (1) · Lymphoma, Follicular (1) · Myelodysplastic Syndromes (1) · Prostatic Neoplasms (1) · Urinary Bladder Neoplasms (1)
City of Hope Medical Center (2) · University of Washington (2) · Alliance for Clinical Trials in Oncology (1) · ECOG-ACRIN Cancer Research Group (1) · Jonsson Comprehensive Cancer Center (1) · M.D. Anderson Cancer Center (1) · National Cancer Institute (NCI) (1) · Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University (1)
United States (9)
Jennifer Johnson, MD, PhD (1) · Lauren Colbert (1) · Lia M. Halasz (1) · Neha Vapiwala (1) · Patrick Y Wen, MD (1) · Rifaquat M. Rahman, MD (1) · Savita V Dandapani (1) · Stephanie M Yoon (1) · T. Martin Ma, MD, PhD (1) · Travis Courtney, MD (1) · Ugonma N Chukwueke, MD (1) · Vaishalee P Kenkre (1)
PMID 37019367, PMID 37536941, PMID 38421243, PMID 39709372
U10CA180820 (2), P30CA033572 (1)