6 completed, 3 terminated. 4 Phase 2, 3 Phase 1, 3 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Completed 2, Terminated 2 |
| Phase 1 | 3 | Completed 2, Terminated 1 |
| Phase 3 | 3 | Completed 3 |
Follow Vincristine sulfate liposome injection: new trials by email Literature Review of Vincristine sulfate liposome injection trials Research Report on Vincristine sulfate liposome injection
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Vincristine Sulfate Liposome Injection (Marqibo®), Bendamustine and Rituximab-Phase I Trial in Indolent B-cell Lymphoma Rituximab, Bendamustine, Vincristine sulfate liposome injection - Lymphoma, Non-Hodgkin, Lymphoma, Follicular | Phase 1 | Completed | Brown University | 11 | 2017-05-10 | 2023-02-09 |
| Re-Induction Therapy for Relapsed Pediatric T-Cell Acute Lymphoblastic Leukemia or Lymphoma Dexamethasone, Panobinostat, Liposomal vincristine - Acute Lymphoblastic Leukemia, Lymphoma, Non-Hodgkin's | Phase 2 | Terminated | St. Jude Children's Research Hospital | 3 | 2016-11-23 | 2019-04-03 |
| Vincristine Sulfate Liposome in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia Vincristine Sulfate Liposome, Laboratory Biomarker Analysis - Recurrent Adult Acute Myeloid Leukemia | Phase 2 | Terminated | Wake Forest University Health Sciences | 5 | 2015-06-05 | 2019-08-14 |
| Combination Chemotherapy and Radiation Therapy in Treating Young Patients With Newly Diagnosed Hodgkin Lymphoma bleomycin sulfate, doxorubicin hydrochloride, liposomal vincristine sulfate - Childhood Nodular Lymphocyte Predominant Hodgkin Lymphoma, Stage III Childhood Hodgkin Lymphoma | Phase 3 | Completed | Children's Oncology Group | 166 | 2009-12-07 | 2022-04-28 |
| Obatoclax Mesylate, Vincristine Sulfate, Doxorubicin Hydrochloride, and Dexrazoxane Hydrochloride in Treating Young Patients With Relapsed or Refractory Solid Tumors, Lymphoma, or Leukemia dexrazoxane hydrochloride, doxorubicin hydrochloride, obatoclax mesylate - Acute Leukemias of Ambiguous Lineage, Acute Undifferentiated Leukemia | Phase 1 | Terminated | National Cancer Institute (NCI) | 22 | 2009-06-01 | 2014-05-01 |
| Bortezomib and Combination Chemotherapy in Treating Young Patients With Relapsed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma L-asparaginase, doxorubicin hydrochloride, therapeutic hydrocortisone - B-cell Adult Acute Lymphoblastic Leukemia, B-cell Childhood Acute Lymphoblastic Leukemia | Phase 2 | Completed | National Cancer Institute (NCI) | 148 | 2009-03-01 | 2017-01-27 |
| Systemic Chemotherapy and Subtenon Carboplatin, and Local Ophthalmic Therapy in Children With Intraocular Retinoblastoma liposomal vincristine sulfate, cryosurgery, laser surgery - Intraocular Retinoblastoma | Phase 3 | Completed | Children's Oncology Group | 30 | 2007-04-16 | 2021-07-30 |
| Vincristine, Carboplatin, and Etoposide or Observation Only in Treating Patients Who Have Undergone Surgery for Newly Diagnosed Retinoblastoma liposomal vincristine sulfate, carboplatin, etoposide - Intraocular Retinoblastoma | Phase 3 | Completed | Children's Oncology Group | 331 | 2005-12-01 | 2021-02-18 |
| Chemoimmunotherapy With Epratuzumab in Relapsed Acute Lymphoblastic Leukemia (ALL) L-asparaginase, doxorubicin hydrochloride, therapeutic hydrocortisone - Recurrent Childhood Acute Lymphoblastic Leukemia | Phase 1 / Phase 2 | Completed | Children's Oncology Group | 134 | 2005-02-01 | 2017-12-12 |
Precursor Cell Lymphoblastic Leukemia-Lymphoma (4) · Leukemia, Lymphocytic, Chronic, B-Cell (2) · Lymphoma, Non-Hodgkin (2) · Blast Crisis (1) · Burkitt Lymphoma (1) · Dendritic Cell Sarcoma, Interdigitating (1) · Hodgkin Disease (1) · Immunoblastic Lymphadenopathy (1) · Intraocular Lymphoma (1) · Leukemia, B-Cell (1) · Leukemia, Biphenotypic, Acute (1) · Leukemia, Hairy Cell (1) · Leukemia, Myeloid, Acute (1) · Leukemia, T-Cell (1) · Lymphoma, B-Cell, Marginal Zone (1)
Children's Oncology Group (4) · National Cancer Institute (NCI) (2) · Brown University (1) · St. Jude Children's Research Hospital (1) · Wake Forest University Health Sciences (1)
United States (9) · Canada (5) · Australia (4) · Puerto Rico (3) · India (1) · Israel (1) · New Zealand (1)
Adam J Olszewski, MD (1) · Elizabeth Raetz, MD (1) · Kara Kelly, MD (1) · Murali Chintagumpala, MD (1) · Richard Aplenc (1) · Rima Jubran (1) · Sima Jeha, MD (1) · Terzah Horton, MD PhD (1) · Timothy Pardee (1)
PMID 23393050, PMID 28419486, PMID 30957229, PMID 35641232, PMID 37505794, PMID 39969278
U10CA098543 (5), P30CA012197 (1), U01CA097452 (1), U10CA180886 (1)