4 terminated. 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Terminated 4 |
Follow vactosertib: new trials by email Literature Review of vactosertib trials Research Report on vactosertib
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Antitumor Activity of Vactosertib in Combination With Pembrolizumab in Acral and Mucosal Melanoma Patients Progressed From Prior Immune Check Point Inhibitor Pembrolizumab, Vactosertib - Acral Melanoma, Mucosal Melanoma | Phase 2 | Terminated | Yonsei University | 14 | 2023-02-09 | 2025-04-02 |
| Vactosertib in Combination with Pembrolizumab for PD-L1 Positive Non-small Cell Lung Cancer (NSCLC) Subjects Vactosertib 300 mg BID and pembrolizumab 200 mg IV - Carcinoma, Non-Small-Cell Lung | Phase 2 | Terminated | MedPacto, Inc. | 11 | 2020-12-17 | 2024-12-09 |
| Intra-patient Dose Escalation Study to Investigate Safety and Feasibility of Vactosertib in Treating Anemic MPN Patients Vactosertib - Myeloproliferative Neoplasm | Phase 2 | Terminated | Weill Medical College of Cornell University | 2 | 2019-11-22 | 2025-07-02 |
| Preoperative Immunotherapy (Pembrolizumab) for Patients With Colorectal Cancer and Resectable Hepatic Metastases Hepatectomy, Pembrolizumab, Vactosertib - Metastatic Malignant Neoplasm in the Liver, Stage IV Colorectal Cancer AJCC v8 | Phase 2 | Terminated | Chloe Atreya, MD, PhD | 6 | 2019-07-22 | 2025-12-31 |
Anemia (1) · Carcinoma, Non-Small-Cell Lung (1) · Colorectal Neoplasms (1) · Myeloproliferative Disorders (1)
Chloe Atreya, MD, PhD (1) · MedPacto, Inc. (1) · Weill Medical College of Cornell University (1) · Yonsei University (1)
South Korea (2) · United States (2)
Chloe Atreya, MD, Ph.D. (1) · Joseph M Scandura, MD, PhD (1) · Minkyu Heo (1) · Minkyu Jung (1)