11 completed, 2 not yet recruiting, 1 enrolling by invitation, 1 recruiting. 11 Not applicable, 3 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 11 | Completed 8, Enrolling by invitation 1, Not yet recruiting 1, Unknown 1 |
| Phase 2 | 3 | Not yet recruiting 1, Recruiting 1, Suspended 1 |
| Phase 1 | 1 | Completed 1 |
Follow Twin block: new trials by email Literature Review of Twin block trials Research Report on Twin block
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Reducing Opioid Use and Misuse After Wisdom Molar Extractions Twin block, iPill dispenser - Pain, Postoperative | Phase 2 | Suspended | Rutgers, The State University of New Jersey | 133 | 2026-11-01 | 2026-06-22 |
| Jaw Muscle Pain Post Wisdom Molar Surgery Temporo-masseteric Nerve Block Injection, Oral Pain Medications only - Post Operative Pain, Impacted Third Molar Tooth | Phase 2 | Not yet recruiting | Rutgers, The State University of New Jersey | 80 | 2026-09-01 | 2026-06-18 |
| Comparison of Early Interceptive Orthodontic Appliances (Traditional and Novel) and Later Fixed Appliance Treatment in Class II Malocclusion. Head gear activator, Twin Block, Invisalign mandibular advancement - Class II Malocclusion, Class II Malocclusion, Division 1 | Not applicable | Not yet recruiting | Vastra Gotaland Region | 144 | 2026-01-15 | 2026-02-11 |
| Three-Dimensional Evaluation of Pharyngeal Airway and Facial Dimension Changes in Skeletal Class II Patients Treated With Twin Block Versus Myobrace Appliances myobrace appliance, Twin block - Class II Division 1 Adolescent Patients | Not applicable | Enrolling by invitation | University of Baghdad | 50 | 2025-05-20 | 2025-05-16 |
| Conventional Versus 3D Printed Twin Block Appliances in Growth Modification of Class II Malocclusion Twin Block - Class II Malocclusion | Completed | Al-Azhar University | 20 | 2024-04-01 | 2026-08-31 | |
| Comparative Effect of Conventional and 3D-printed Twin Block Appliances on Soft Tissue Changes Twin Block - Class II Malocclusion | Phase 1 | Completed | Al-Azhar University | 20 | 2024-01-01 | 2026-09-01 |
| Assesment of Tempromandibular Joint ( TMJ ) Changes After Treatment of Skeletal Class II Cases by Twinblock vs Monoblock Appliances twin block, Mono block - Skeletal Class II Malocclusion | Not applicable | Completed | Faculty of Dental Medicine for Girls | 18 | 2023-08-15 | 2025-12-08 |
| The Effect of Low-level Laser Therapy on Functional Treatment of Skeletal Class II Patients twin block, twin block combined with low level laser - Class II Malocclusion | Not applicable | Completed | Mansoura University | 24 | 2022-10-26 | 2024-03-13 |
| Comparison Between Mandibular Advancement With Aligners and Twin Block in Class II Malocclusion in Growing Patients AngelAligner A6 Mandibular Advancer, Twin Block, Clear aligners - Malocclusion Class II | Not applicable | Completed | University of Salamanca | 60 | 2022-10-18 | 2026-05-15 |
| Characterization of the Temporo-masseteric Nerve Block (TMNB) in Healthy Subjects Temporomasseteric Nerve Block - Occlusion | Phase 2 | Recruiting | Rutgers, The State University of New Jersey | 20 | 2022-10-10 | 2025-12-05 |
| Pharyngeal Airway Dimensions With Twinblock Versus Myobrace Appliances in Developing Skeletal Class II Patients Myobrace Functional Appliance, Twin Block - Malocclusion, Angle Class II, Division 1 | Not applicable | Completed | Alexandria University | 26 | 2022-04-01 | 2024-02-01 |
| Comparative Effect of Clear Aligner Mandibular Advancement and Twin Block Appliances in Class II Malocclusion Twin block, Clear aligner with mandibular function - CLASS II DIVISION 1 MALOCCLUSION | Completed | Sichuan University | 47 | 2021-08-01 | 2024-09-24 | |
| Effects of Orthopedic Mandibular Advancement in Class II Division 1 Malocclusion on Pharyngeal Airway Twin Block, Fixed orthodontic appliance - ClassII Division 1 Malocclusion, Mandibular Retrognathism | Not applicable | Completed | Mansoura University | 50 | 2019-12-10 | 2021-12-07 |
| Treatment Adherence With Twin-Blocks for Correction of Class II Malocclusion Twin block - Compliance, Patient, Treatment Adherence | Not applicable | Completed | Region Jönköping County | 73 | 2018-12-01 | 2022-01-11 |
| The Effect of Functional Treatment of Patients With Backward Positioned Chins on the Jaw Joint and Movements Activator, Twin Block - Malocclusion, Angle Class II, Retrognathism | Not applicable | Completed | Damascus University | 66 | 2018-06-15 | 2020-02-05 |
| Predictors Associated With Seeking Orthodontic Treatment, Compliance and Treatment Success Twin Block, Sander bite jumping appliance - Malocclusion, Angle Class II | Not applicable | Completed | Visnja Katic | 110 | 2015-02-09 | 2022-05-26 |
| Study to Measure the Effect of Part Time Versus Full Time Orthodontic Appliance Wear Modified Clark Twin Block - Class II Division 1 Malocclusion | Not applicable | Unknown | Queen Mary University of London | 62 | 2013-12-01 | 2017-01-04 |
Malocclusion, Angle Class II (7) · Overbite (4) · Pain, Postoperative (2) · Bites and Stings (1) · Myalgia (1) · Patient Compliance (1) · Retrognathia (1) · Treatment Adherence and Compliance (1)
Rutgers, The State University of New Jersey (3) · Al-Azhar University (2) · Mansoura University (2) · Alexandria University (1) · Damascus University (1) · Faculty of Dental Medicine for Girls (1) · Queen Mary University of London (1) · Region Jönköping County (1) · Sichuan University (1) · University of Baghdad (1) · University of Salamanca (1) · Vastra Gotaland Region (1) · Visnja Katic (1)
Egypt (6) · United States (3) · Sweden (2) · China (1) · Croatia (1) · Iraq (1) · Spain (1) · Syria (1) · United Kingdom (1)
Abdulmalek Majanni, DDS MSc (1) · Ahmed Median, PhD (1) · Anayo Adachie, DMD, MD (1) · Anders Magnusson, DDS, DMSc (1) · Anna Westerlund, Professor (1) · Eman S Radwan, MSc (1) · Gayathri D Subramanian, DMD (1) · Gayathri Subramanian, PhD DMD (1) · Issam Khoury, DDS MSc PhD (1) · Jeet Parekh, BDS (1) · Kate Counihan, BDS (1) · Lubna M Hussein, B.D.S., M.Sc. (Orthodontics) (1) · Mikael Sonesson, DDS, DMSc (1) · Mohammad Y Hajeer, DDS MSc PhD (1) · Mona A Montasser, Phd (1)
PMID 30712687, PMID 31118532, PMID 31444594, PMID 34402117, PMID 35094890, PMID 35968672, PMID 37522361, PMID 41211711, PMID 42773450