Tumor Necrosis Factor: Clinical Trials

6 trials of Tumor Necrosis Factor, newest first

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6 completed. 2 Phase 2, 2 Phase 3, 1 Phase 1.

By phase and status

PhaseTrialsStatus
Phase 22Completed 2
Phase 32Completed 2
Phase 11Completed 1

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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Host Dysregulation-Driven Sepsis Prediction Model
Tumor Necrosis Factor, Interleukin-1β, Interleukin-12 - Sepsis
CompletedSecond Affiliated Hospital of Wenzhou Medical University10002024-09-012024-10-31
Isolated Limb Perfusion of Melphalan With or Without Tumor Necrosis Factor in Treating Patients With Soft Tissue Sarcoma of the Arm or Leg
melphalan, tumor necrosis factor - Stage IVB Adult Soft Tissue Sarcoma, Stage IIB Adult Soft Tissue Sarcoma
Phase 2CompletedNational Institutes of Health Clinical Center (CC)1999-08-012023-10-31
Melphalan With or Without Tumor Necrosis Factor in Treating Patients With Locally Advanced Melanoma of the Arm or Leg
isolated limb perfusion, melphalan, recombinant tumor necrosis factor family protein - Recurrent Melanoma, Stage III Melanoma
Phase 3CompletedNational Cancer Institute (NCI)2161999-03-012013-07-16
A Randomized Phase III Trial of Hyperthermic Isolated Limb Perfusion With Melphalan, Tumor Necrosis Factor, and Interferon-Gamma in Patients With Locally Advanced Extremity Melanoma
melphalan, tumor necrosis factor, interferon-gamma - Melanoma
Phase 3CompletedNational Cancer Institute (NCI)1221992-02-012008-03-04
A Study of Tumor Necrosis Factor and Human Interferon-gamma in Patients With AIDS Related Complex
Tumor Necrosis Factor, Interferon gamma-1b - HIV Infections
Phase 2CompletedNational Institute of Allergy and Infectious Diseases (NIAID)302021-11-04
A Phase I/II Study of Intralesional Recombinant Tumor Necrosis Factor in Patients With AIDS-Related Cutaneous Kaposi's Sarcoma
Tumor Necrosis Factor - Sarcoma, Kaposi, HIV Infections
Phase 1CompletedUniversity of California, San Francisco2005-06-24

Conditions studied

Acquired Immunodeficiency Syndrome (2)  ·  HIV Infections (2)  ·  Melanoma (2)  ·  AIDS-Related Complex (1)  ·  Muscle Neoplasms (1)  ·  Neoplasms (1)  ·  Sarcoma (1)  ·  Sarcoma, Kaposi (1)  ·  Sepsis (1)  ·  Skin Neoplasms (1)

Sponsors

National Cancer Institute (NCI) (2)  ·  National Institute of Allergy and Infectious Diseases (NIAID) (1)  ·  National Institutes of Health Clinical Center (CC) (1)  ·  Second Affiliated Hospital of Wenzhou Medical University (1)  ·  University of California, San Francisco (1)

Countries

United States (4)  ·  China (1)

Top investigators

Corey L (1)  ·  Douglas Fraker (1)  ·  H. Richard Alexander, Jr. (1)  ·  Kaplan L (1)

NIH funding

U10CA076001 (1)