5 completed, 1 withdrawn. 3 Phase 1, 2 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Completed 3 |
| Phase 2 | 2 | Completed 1, Withdrawn 1 |
| Phase 3 | 1 | Completed 1 |
Follow tocophersolan: new trials by email Literature Review of tocophersolan trials Research Report on tocophersolan
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Use of Tocofersolan (Vedrop®) to Prevent or Treat Refractive Vitamin E Deficiency in Infants and Children Tocofersolan - Short Bowel Syndrome, Vitamin E Deficiency | Phase 2 | Withdrawn | Boston Children's Hospital | 2020-12-01 | 2020-05-13 | |
| Bioavailability Study of Oral OZ439 Prototype Granule Formulations Administered With Piperaquine Phosphate (PQP) Tablets OZ439 + TPGS, OZ439 Prototype 1, OZ439 Prototype 3 - Malaria | Phase 1 | Completed | Medicines for Malaria Venture | 48 | 2015-04-01 | 2016-02-08 |
| Open Label Pharmacokinetic Study of OZ439 and Piperaquine on Administration of OZ439+TPGS Granules for Oral Suspension Alone or With Either Piperaquine Phosphate Tablets or Granules for Oral Solution in Healthy Volunteers 1440mg PQP tablets, 960mg PQP tablets, 800mg OZ439 + TPGS - Malaria | Phase 1 | Completed | Medicines for Malaria Venture | 55 | 2013-10-01 | 2015-05-08 |
| Vitamin E Supplement in Patients With Cirrhosis and Acanthocytosis Vitamin E supplement (tocofersolan) - Cirrhosis | Phase 2 | Completed | University Hospital, Geneva | 27 | 2011-11-01 | 2014-03-18 |
| Study of the Absorption of Vitamin E Water-soluble Form (Pegylated) in the Familial Hypocholesterolemia With Chylomicron Retention Tocofersolan, tocopherol alpha, Tocofersolan and tocopherol alpha - Hypobetalipoproteinemias | Phase 3 | Completed | Hospices Civils de Lyon | 14 | 2011-10-01 | 2025-08-22 |
| Combination Therapy With Oral 9-Nitrocamptothecin & Oral Etoposide Oral Etoposide, Oral 9-Nitrocamptothecin - Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 | Completed | H. Lee Moffitt Cancer Center and Research Institute | 44 | 2000-06-01 | 2012-09-26 |
Malaria (2) · Fibrosis (1) · Hypobetalipoproteinemias (1) · Short Bowel Syndrome (1) · Vitamin E Deficiency (1)
Medicines for Malaria Venture (2) · Boston Children's Hospital (1) · H. Lee Moffitt Cancer Center and Research Institute (1) · Hospices Civils de Lyon (1) · University Hospital, Geneva (1)
United Kingdom (2) · France (1) · Switzerland (1) · United States (1)
Daniel M. Sullivan, M.D. (1) · Fiona Macintyre, PhD (1) · Ulrike Lorch, MD FRCA FFPM (1)