3 recruiting, 1 active not recruiting. 4 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Recruiting 3, Active not recruiting 1 |
| Phase 2 | 1 | Active not recruiting 1 |
Follow Thymidine: new trials by email Literature Review of Thymidine trials Research Report on Thymidine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Nucleoside Therapy in Patients With Telomere Biology Disorders deoxycytidine, deoxythymidine - Telomere Biology Disorders, Dyskeratosis Congenita | Phase 1 | Recruiting | Suneet Agarwal | 36 | 2025-09-29 | 2026-08-04 |
| Beta-blocker Administration for Cardiomyocyte Division N-thymidine, Urine Collection, Echocardiogram - Tetralogy of Fallot, Double Outlet Right Ventricle | Phase 1 | Recruiting | Weill Medical College of Cornell University | 40 | 2022-12-16 | 2026-10-26 |
| Trifluridine/Tipiracil and Talazoparib for the Treatment of Patients With Locally Advanced or Metastatic Colorectal or Gastroesophageal Cancer Trifluridine and Tipiracil Hydrochloride, Talazoparib Tosylate - Advanced Malignant Solid Neoplasm, Clinical Stage III Gastroesophageal Junction Adenocarcinoma | Phase 1 | Recruiting | Roswell Park Cancer Institute | 45 | 2021-06-08 | 2026-05-04 |
| Treatment of TK2 Deficiency With Thymidine and Deoxycytidine Thymidine - Mitochondrial DNA Depletion Syndrome 2 Myopathic Type, Thymidine Kinase 2 Deficiency | Phase 1 / Phase 2 | Active not recruiting | Columbia University | 23 | 2017-05-16 | 2026-01-28 |
Bone Marrow Failure Disorders (1) · Colorectal Neoplasms (1) · Double Outlet Right Ventricle (1) · Dyskeratosis Congenita (1) · Hoyeraal Hreidarsson syndrome (1) · Pulmonary Fibrosis (1) · Revesz Debuse syndrome (1) · Tetralogy of Fallot (1)
Columbia University (1) · Roswell Park Cancer Institute (1) · Suneet Agarwal (1) · Weill Medical College of Cornell University (1)
United States (4)
Bernhard Kuhn, MD (1) · Christos Fountzilas, MD (1) · Helen Reed, MD, MPH (1) · Michio Hirano, MD (1)
PMID 23932787, PMID 24968719, PMID 28318037, PMID 29602790, PMID 34265312
R01HL155597 (1), R37CA282430 (1)