5 completed. 5 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 5 | Completed 5 |
Follow TB-403: new trials by email Literature Review of TB-403 trials Research Report on TB-403
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of TB-403 in Pediatric Subjects With Relapsed or Refractory Medulloblastoma TB-403 20mg/kg, TB-403 50mg/kg, TB-403 100mg/kg - Relapsed or Refractory Medulloblastoma (MB), Neuroblastoma (NB), Ewing Sarcoma (ES) and Alveolar Rhabdomyosarcoma (ARMS) | Phase 1 | Completed | Oncurious NV | 18 | 2016-05-01 | 2021-01-13 |
| A Dose- and Efficacy-Finding Study of RO5323441 in Combination With Avastin (Bevacizumab) in Patients With Recurrent Glioblastoma RO5323441 + bevacizumab [Avastin], bevacizumab [Avastin] - Glioblastoma Multiforme | Phase 1 | Completed | Hoffmann-La Roche | 22 | 2011-05-01 | 2016-11-02 |
| A Dose-Finding and Exploratory Study of RO5323441 in Combination With Sorafenib in Patients With Hepatocellular Carcinoma RO5323441, sorafenib - Carcinoma, Hepatocellular | Phase 1 | Completed | Hoffmann-La Roche | 6 | 2011-03-01 | 2016-11-02 |
| A Dose-finding Study of RO5323441 in Patients With Metastatic Treatment-Refractory Colorectal or Ovarian Cancer RO5323441 - Colorectal Cancer, Ovarian Cancer | Phase 1 | Completed | Hoffmann-La Roche | 7 | 2010-05-01 | 2016-11-02 |
| Phase I Study on Monoclonal Antibody TB-403 Directed Against PlGF in Patients With Solid Tumours TB-403 - Solid Tumors | Phase 1 | Completed | BioInvent International AB | 21 | 2008-06-01 | 2022-03-16 |
Carcinoma, Hepatocellular (1) · Colorectal Neoplasms (1) · Glioblastoma (1) · Medulloblastoma (1) · Neuroblastoma (1) · Ovarian Neoplasms (1) · Recurrence (1) · Rhabdomyosarcoma, Alveolar (1) · Sarcoma, Ewing (1)
Hoffmann-La Roche (3) · BioInvent International AB (1) · Oncurious NV (1)
Denmark (2) · United Kingdom (2) · Belgium (1) · France (1) · Singapore (1) · Spain (1) · Switzerland (1) · United States (1)
Dorthe Nielsen, MD, PhD (1) · Lena Winstedt, PhD (1) · Ulrik Lassen, MD, PhD (1)
2009 (1)