9 completed, 8 terminated, 1 withdrawn. 13 Phase 3, 3 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 13 | Terminated 7, Completed 5, Withdrawn 1 |
| Phase 2 | 3 | Completed 2, Terminated 1 |
| Phase 1 | 2 | Completed 2 |
Follow TAK-875: new trials by email Literature Review of TAK-875 trials Research Report on TAK-875
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Fasiglifam in Type 2 Diabetic Subjects With Chronic Kidney Disease Stage 4 or 5 on Hemodialysis Fasiglifam, Placebo, Antihyperglycemic therapy - Type 2 Diabetes Mellitus, Chronic Kidney Disease | Phase 3 | Withdrawn | Takeda | 2013-12-01 | 2014-01-27 | |
| Fasiglifam 25 mg BID vs 50 mg QD Fasiglifam, Placebo to fasiglifam - Type 2 Diabetes Mellitus | Phase 2 | Terminated | Takeda | 10 | 2013-10-01 | 2016-10-07 |
| Comparison of Fasiglifam (TAK-875) With Sitagliptin When Used in Combination With Metformin in Patients With Type 2 Diabetes Fasiglifam (TAK-875), Fasiglifam (TAK-875) Placebo, Sitagliptin - Diabetes Mellitus, Type 2 | Phase 3 | Terminated | Takeda | 96 | 2013-06-01 | 2015-09-28 |
| TAK-875 (Fasiglifam) in Combination With Sitagliptin in Adults With Type 2 Diabetes Placebo, TAK-875 - Diabetes | Phase 3 | Terminated | Takeda | 90 | 2013-05-01 | 2016-06-01 |
| Comparison of TAK-875 to Placebo as an Add-on to Glimepiride in Patients With Type 2 Diabetes TAK-875, TAK-875 Placebo, Glimepiride - Diabetes Mellitus, Type 2 | Phase 3 | Terminated | Takeda | 33 | 2013-04-01 | 2016-06-01 |
| Study to Evaluate the Efficacy and Safety of Daily Oral TAK-875 25 and 50mg in Asia Pacific Adults With Type 2 Diabetes TAK-875, TAK-875 Placebo - Type 2 Diabetes Mellitus | Phase 3 | Terminated | Takeda | 393 | 2012-10-01 | 2015-11-11 |
| Study of TAK-875 in Adults With Type 2 Diabetes and Cardiovascular Disease or Risk Factors for Cardiovascular Disease TAK-875, TAK-875 Placebo - Type 2 Diabetes, Cardiovascular Disease | Phase 3 | Terminated | Takeda | 3207 | 2012-06-01 | 2015-10-19 |
| Double Blind Comparative Study of TAK-875 TAK-875, Glimepiride, Placebo - Diabetic Patients | Phase 3 | Completed | Takeda | 80 | 2012-05-01 | 2013-04-16 |
| Comparison of Fasiglifam (TAK-875) to Placebo and Sitagliptin in Combination With Metformin in Participants With Type 2 Diabetes Fasiglifam (TAK-875), Sitagliptin, Placebo - Glycemic Control | Phase 3 | Terminated | Takeda | 916 | 2012-04-01 | 2016-06-02 |
| Efficacy and Safety of TAK-875 Compared to Glimepiride When Used With Metformin in Participants With Type 2 Diabetes TAK-875, Glimepiride - Diabetes Mellitus, Type 2 | Phase 3 | Terminated | Takeda | 2454 | 2012-01-01 | 2016-06-01 |
| TAK-875 Glimepiride Drug-Interaction Study TAK-875 and Glimepiride - Pharmacokinetics | Phase 1 | Completed | Takeda | 28 | 2012-01-01 | 2012-09-13 |
| Open-label Study of TAK-875 TAK-875 - Diabetes Mellitus | Phase 3 | Completed | Takeda | 333 | 2012-01-01 | 2013-03-22 |
| Comparison of TAK-875 (Fasiglifam) With Placebo in Participants With Type 2 Diabetes Placebo, Fasiglifam - Diabetes Mellitus, Type 2 | Phase 3 | Completed | Takeda | 421 | 2011-11-01 | 2016-04-05 |
| Long-term Study of TAK-875 TAK-875 - Diabetes Mellitus | Phase 3 | Completed | Takeda | 1222 | 2011-10-01 | 2014-01-27 |
| Efficacy and Safety of TAK-875 in Combination With Sitagliptin in Participants With Type 2 Diabetes Mellitus Placebo, TAK-875, Sitagliptin - Diabetes Mellitus, Type 2 | Phase 2 | Completed | Takeda | 368 | 2011-08-01 | 2016-04-04 |
| Efficacy and Safety of TAK-875 in Subjects With Type 2 Diabetes Mellitus TAK-875, Glimepiride, Placebo - Diabetes Mellitus, Type 2 | Phase 2 | Completed | Takeda | 426 | 2009-12-01 | 2016-04-13 |
| Pharmacokinetics and Pharmacodynamics of TAK-875 in Subjects With Type 2 Diabetes TAK-875 - Diabetes Mellitus, Type 2 | Phase 1 | Completed | Takeda | 60 | 2009-01-01 | 2010-06-11 |
| Double-blind Comparative Study of TAK-875 TAK-875, Placebo - Diabetes Mellitus | Phase 3 | Completed | Takeda | 192 | 2012-11-09 |
Diabetes Mellitus, Type 2 (11) · Diabetes Mellitus (4) · Cardiovascular Diseases (1) · Renal Insufficiency, Chronic (1)
Takeda (18)
United States (12) · Bulgaria (7) · Hungary (6) · Poland (6) · Slovakia (6) · Ukraine (6) · Argentina (5) · Australia (4) · Canada (4) · Japan (4) · Malaysia (4) · Mexico (4) · Romania (4) · South Africa (4) · Taiwan (4)