7 completed, 1 terminated. 5 Phase 1, 4 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 5 | Completed 5 |
| Phase 2 | 4 | Completed 3, Terminated 1 |
| Phase 3 | 1 | Completed 1 |
Follow this drug Literature Review of SPH3127 trials Research Report on SPH3127
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of SPH3127 in the Treatment of Mild to Moderate Ulcerative Colitis SPH3127 Tablets with Dose A, SPH3127 Tablets with Dose B, SPH3127 Tablets placebo - Mild to Moderate Ulcerative Colitis | Phase 2 | Completed | Shanghai Pharmaceuticals Holding Co., Ltd | 53 | 2023-06-19 | 2025-08-28 |
| Study on Human Mass Balance of SPH3127 Tablets SPH3127 - Primary Mild and Moderate Hypertension | Phase 1 / Phase 2 | Completed | Shanghai Pharmaceuticals Holding Co., Ltd | 6 | 2022-10-16 | 2022-12-07 |
| Evaluation of SPH3127 in Patients With Mild-to-Moderate Ulcerative Colitis SPH3127, Placebo - Ulcerative Colitis | Phase 2 | Terminated | Shanghai Pharma Biotherapeutics USA Inc. | 3 | 2022-03-21 | 2025-06-26 |
| Drug-drug Interaction Study of SPH3127 SPH3127 tablet, Itraconazole, Rifampin - Drug Drug Interaction | Phase 1 / Phase 2 | Completed | Shanghai Pharmaceuticals Holding Co., Ltd | 40 | 2021-12-13 | 2022-07-29 |
| Study to Evaluate the Efficacy and Safety of SPH3127 In Patients With Mild-moderate Essential Hypertension SPH3127 tablet, Valsartan - Essential Hypertension | Phase 3 | Completed | Shanghai Pharmaceuticals Holding Co., Ltd | 957 | 2021-06-10 | 2024-05-07 |
| The Tolerability and Pharmacokinetics of Multiple Doses of SPH3127 in Chinese Healthy People SPH3127 50mg, SPH3127 100mg, Placebo matching to SPH3127 50mg - Hypertension | Phase 1 | Completed | Shanghai Pharmaceuticals Holding Co., Ltd | 24 | 2017-10-23 | 2021-11-15 |
| The Effect of Food Intake on the Pharmacokinetic of Single Dose SPH3127 Tablets in Chinese Health Subjects SPH3127 200mg Panel A, SPH3127 200mg Panel B - Hypertension | Phase 1 | Completed | Shanghai Pharmaceuticals Holding Co., Ltd | 20 | 2017-09-23 | 2021-11-15 |
| Single Ascending Dose Study of Safety and Tolerability of SPH3127 Tablet in Chinese Healthy Volunteers SPH3127 - Hypertension | Phase 1 | Completed | Shanghai Pharmaceuticals Holding Co., Ltd | 48 | 2016-12-01 | 2022-10-27 |
Hypertension (3) · Colitis, Ulcerative (1) · Essential Hypertension (1)
Shanghai Pharmaceuticals Holding Co., Ltd (7) · Shanghai Pharma Biotherapeutics USA Inc. (1)
China (7) · United States (1)
Changsheng Ma (1) · Kenneth W. Locke, PhD (1) · Qin Yu (1)