6 unknown, 3 completed. 6 Phase 3, 3 Phase 2, 1 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 6 | Unknown 5, Completed 1 |
| Phase 2 | 3 | Completed 2, Unknown 1 |
| Early Phase 1 | 1 | Completed 1 |
Follow SIB-IMRT: new trials by email Literature Review of SIB-IMRT trials Research Report on SIB-IMRT
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Neoadjuvant Chemotherapy With PD-1 Inhibitors Combined With SIB-IMRT in the Treatment of Locally Advanced Rectal Cancer Tislelizumab, Capecitabine, Oxaliplatin - Rectal Neoplasms | Phase 3 | Unknown | Yong Zhang,MD | 48 | 2023-09-01 | 2023-10-11 |
| A Phase II Study of Total Neoadjuvant Therapy for Locally Advanced Gastric Cancer SIB-IMRT, S-1, SOX - Gastric Cancer, Neoadjuvant Therapy | Phase 2 | Unknown | Jing Jin, M.D. | 82 | 2019-11-20 | 2022-01-24 |
| Radiotherapy With or Without Concurrent Chemotherapy for Limited Lymphatic Metastasis of Esophageal Cancer - 3JECROG P-02 SIB-IMRT, Paclitaxel, Platinum-Based Drug - Esophageal Neoplasms | Phase 3 | Unknown | Chinese Academy of Medical Sciences | 164 | 2017-12-01 | 2019-01-02 |
| Radiotherapy With or Without Concurrent Chemotherapy for Extensive Lymphatic Metastasis of Esophageal Cancer - 3JECROG P-03 SIB-IMRT, Paclitaxel, Platinum-Based Drug - IMRT With or Without Concurrent Chemotherapy for Esophageal Cancer | Phase 3 | Unknown | Chinese Academy of Medical Sciences | 2 | 2017-09-01 | 2019-01-02 |
| Simultaneous Integrated Boost vs. Routine IMRT in Limited-stage Small-cell Lung Cancer SIB-IMRT, routine IMRT - Small-cell Lung Cancer | Phase 3 | Unknown | Chinese Academy of Medical Sciences | 350 | 2017-07-20 | 2021-02-01 |
| Nivolumab, Ipilimumab, and Radiation Therapy in Treating Patients With Stage III-IVB Head and Neck Cancer Nivolumab, Ipilimumab, Simultaneous-Integrated Boost Intensity-Modulated Radiation Therapy - Larynx, Lip, Oral Cavity and Pharynx | Early Phase 1 | Completed | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University | 24 | 2017-05-11 | 2025-04-29 |
| Phase II/III Study Comparing Chemoradiotherapy With Radiotherapy in Elderly Patients With Esophageal or Esophagogastric Cancer - 3JECROG P-01 SIB-IMRT, S-1 - Esophagus Cancer, Esophagogastric Junction Cancer | Phase 2 / Phase 3 | Completed | Chinese Academy of Medical Sciences | 350 | 2016-10-01 | 2020-07-21 |
| A Randomized Phase II Trial of Neoadjuvant Chemotherapy Compared With Chemoradiotherapy in Gastric Adenocarcinoma SIB-IMRT, S-1, Surgery - Stomach Neoplasms, Neoadjuvant Therapy | Phase 2 | Completed | Chinese Academy of Medical Sciences | 71 | 2014-01-01 | 2019-10-16 |
| The Role of Concurrent Chemotherapy for Lower Risk Locally Advanced Nasopharyngeal Carcinoma(NPC) in the Era of IMRT SIB-IMRT, Cisplatin - Nasopharyngeal Carcinoma | Phase 3 | Unknown | Chinese Academy of Medical Sciences | 590 | 2013-04-01 | 2021-01-29 |
Esophageal Neoplasms (2) · Stomach Neoplasms (2) · Laryngeal Diseases (1) · Lymphoid Interstitial Pneumonia (1) · Nasopharyngeal Carcinoma (1) · Rectal Neoplasms (1) · Small Cell Lung Carcinoma (1)
Chinese Academy of Medical Sciences (6) · Jing Jin, M.D. (1) · Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University (1) · Yong Zhang,MD (1)
China (8) · United States (1)
Jennifer Johnson, MD, PhD (1) · Li Gao, MD (1) · Zefen Xiao, MD (1)
PMID 31036088, PMID 32962674, PMID 32983991, PMID 35219300, PMID 35574368, PMID 35902798, PMID 37019367, PMID 37195667, PMID 37536941, PMID 38553594