3 completed, 1 recruiting, 1 terminated. 5 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Completed 3, Recruiting 1, Terminated 1 |
| Phase 1 | 2 | Completed 1, Recruiting 1 |
Follow seviteronel: new trials by email Literature Review of seviteronel trials Research Report on seviteronel
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Seviteronel in Combination With Chemotherapy in Androgen-receptor Positive Metastatic Triple-negative Breast Cancer Seviteronel-D (Seivteronel in combination with dexamethasone), Docetaxel - Triple Negative Breast Cancer | Phase 1 / Phase 2 | Recruiting | St Vincent's Hospital, Sydney | 65 | 2022-11-01 | 2025-05-15 |
| Activity of Seviteronel in Patients With Androgen Receptor (AR)-Positive Glioblastoma SEVI-D (Seviteronel in combination with dexamthasone) - Solid Tumor, Androgen Receptor Gene Overexpression | Phase 2 | Terminated | St Vincent's Hospital, Sydney | 4 | 2018-08-13 | 2021-03-05 |
| CYP17 Lyase and Androgen Receptor Inhibitor Treatment With Seviteronel Trial (INO-VT-464-006; NCT02580448) Seviteronel - Cancer of the Breast, Breast Cancer | Phase 1 / Phase 2 | Completed | Innocrin Pharmaceutical | 175 | 2015-08-01 | 2019-02-01 |
| Once-daily Oral Seviteronel in Patients With Castration-Resistant Prostate Cancer Progressing on Enzalutamide or Abiraterone. Seviteronel: given orally once daily in 28-day cycles - Prostate Cancer | Phase 2 | Completed | Innocrin Pharmaceutical | 197 | 2015-05-01 | 2019-02-01 |
| Oral VT-464 in Patients With Castration-Resistant Prostate Cancer Previously Treated With Enzalutamide, Androgen Receptor Positive Triple-Negative Breast Cancer Patients, and Men With ER Positive Breast Cancer VT-464: given orally twice daily in 28-day cycles, VT-464: given orally once daily in 28-day cycles - Prostate Cancer | Phase 2 | Completed | Innocrin Pharmaceutical | 17 | 2014-04-01 | 2018-05-07 |
Neoplasm Metastasis (2) · Prostatic Neoplasms (2) · Triple Negative Breast Neoplasms (2) · Breast Neoplasms (1) · Breast Neoplasms, Male (1)
Innocrin Pharmaceutical (3) · St Vincent's Hospital, Sydney (2)
United States (3) · Australia (2)