2 completed, 2 recruiting, 1 terminated. 5 Phase 3.
By phase and status
Follow seltorexant: new trials by email Literature Review of seltorexant trials Research Report on seltorexant
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All 5 trials
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|
A Study of Seltorexant as Monotherapy in Adults and Elderly Participants With Major Depressive Disorder
Seltorexant, Placebo - Depressive Disorder, Major | Phase 3 | Recruiting | 600 | 2026-04-30 | 2026-11-03 |
Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms
Seltorexant, Placebo, Selective Serotonin Reuptake Inhibitor (SSRI)/Serotonin-Norepinephrine Reuptake Inhibitor (SNRI) - Depressive Disorder, Major | Phase 3 | Recruiting | 752 | 2024-07-25 | 2026-11-03 |
A Study of Seltorexant as Adjunctive Therapy to Antidepressants in Adult and Elderly Participants With Major Depressive Disorder With Insomnia Symptoms Who Have Responded Inadequately to Antidepressant and Long-term Safety Extension Treatment With Seltorexant
Seltorexant, Placebo - Depressive Disorder, Major | Phase 3 | Completed | 588 | 2020-09-16 | 2026-05-12 |
A Study of Seltorexant Compared to Quetiapine XR as Adjunctive Therapy to Antidepressants in Adult and Elderly Participants With Major Depressive Disorder With Insomnia Symptoms Who Have Responded Inadequately to Antidepressant Therapy
Seltorexant, Matching placebo to Seltorexant, Quetiapine XR - Depressive Disorder, Major | Phase 3 | Completed | 757 | 2020-09-15 | 2025-08-13 |
A Study of Seltorexant as Adjunctive Therapy to Antidepressants in Adult and Elderly Participants With Major Depressive Disorder With Insomnia Symptoms Who Have Responded Inadequately to Antidepressant Therapy
Seltorexant, Placebo - Depressive Disorder, Major | Phase 3 | Terminated | 212 | 2020-09-15 | 2025-06-04 |
Conditions studied
Depressive Disorder, Major (5)
Sponsors
Janssen Research & Development, LLC (5)
Countries
United States (5) · Argentina (4) · Brazil (3) · Bulgaria (3) · Czechia (3) · Malaysia (3) · Poland (3) · Slovakia (3) · Canada (2) · Colombia (2) · Mexico (2) · Russia (2) · Serbia (2) · Spain (2) · Sweden (2)
NIH funding
2023 (1)