4 completed, 1 not yet recruiting, 1 terminated. 3 Not applicable, 1 Phase 2, 1 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 3 | Completed 2, Not yet recruiting 1 |
| Phase 2 | 1 | Completed 1 |
| Phase 3 | 1 | Terminated 1 |
| Phase 4 | 1 | Completed 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Cold Application and Artificial Saliva in the Prevention of Chemotherapy-Induced Oral Mucositis cold application, Artificial Saliva - Oral Mucositis | Not applicable | Not yet recruiting | Karbala University | 60 | 2026-01-01 | 2025-12-26 |
| Evaluation of an Oral Care Kit for Maintaining the Oral Health of Patients Admitted to the Intensive Care Unit Oral Care Kit, Artificial Saliva - Xerostomia, Hyposalivation | Not applicable | Completed | Hospital Israelita Albert Einstein | 82 | 2022-10-25 | 2026-04-29 |
| Efficacy of Oral Moisturizing Jelly on Oral Health and Nutrition in Post-radiotherapy Head and Neck Cancer Patients Oral moisturizing jelly, Artificial saliva - Cancer of Head Neck, Radiation-Induced Xerostomia | Not applicable | Completed | Dental Innovation Foundation Under Royal Patronage | 73 | 2017-03-01 | 2019-02-08 |
| Caphosol Study: Prevention of Oral Mucositis in Children, Adolescents and Young Adults Receiving Chemotherapy Caphosol, Biotene - Oral Mucositis | Phase 3 | Terminated | Medical College of Wisconsin | 1 | 2016-10-01 | 2020-03-09 |
| Efficacy of Traditional Persian Medicine Preparation Versus Artificial Saliva for Radiation Induced Xerostomia mixed powder of A. digitata and M. sylvestris, Hypozalix spray (artificial saliva) - Xerostomia, Head and Neck Cancers | Phase 2 | Completed | Shiraz University of Medical Sciences | 60 | 2015-03-01 | 2016-08-03 |
| A Comparison of Orally Pilocarpine and Artificial Saliva in Xerostomy Treatment pilocarpine, Artificial Saliva - Primary Sjogren, Secondary Sjogren | Phase 4 | Completed | Pontificia Universidad Catolica de Chile | 76 | 2006-11-01 | 2008-05-22 |
Xerostomia (4) · Head and Neck Neoplasms (2) · Stomatitis (2) · Neoplasms (1)
Dental Innovation Foundation Under Royal Patronage (1) · Hospital Israelita Albert Einstein (1) · Karbala University (1) · Medical College of Wisconsin (1) · Pontificia Universidad Catolica de Chile (1) · Shiraz University of Medical Sciences (1)
Brazil (1) · Chile (1) · Thailand (1) · United States (1)
Aroonwan Lam-ubol, DDS, PhD (1) · Batool A Ahmed, MSc (1) · Cristian Vera-Kellet, MD (1) · Fernanda de Paula Eduardo (1) · Michael E Burke, MD (1)
PMID 16424527, PMID 16700739, PMID 16759558, PMID 17000452, PMID 28494850, PMID 31732852, PMID 32779011, PMID 42416311