5 completed, 1 unknown. 3 Phase 2, 2 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Completed 3 |
| Phase 3 | 2 | Completed 2 |
| Phase 1 | 1 | Unknown 1 |
Follow rhC1INH: new trials by email Literature Review of rhC1INH trials Research Report on rhC1INH
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| RUCONEST® as a Therapeutic Strategy to Reduce the Incidence of Delayed Graft Function rhC1INH, Saline Solution - Kidney Failure | Phase 1 | Unknown | University of Wisconsin, Madison | 20 | 2019-06-21 | 2020-12-14 |
| Patient Registry to Evaluate the Real-world Safety of Ruconest® rhC1INH - Hereditary Angioedema | Completed | Pharming Technologies B.V. | 152 | 2018-06-30 | 2024-04-05 | |
| A Phase 2 HAE Prophylaxis Study With Recombinant Human C1 Inhibitor Recombinant human C1 inhibitor, Placebo - Hereditary Angioedema | Phase 2 | Completed | Pharming Technologies B.V. | 32 | 2014-12-01 | 2017-12-08 |
| Safety of Ruconest in 2-13 Year Old Hereditary Angioedema (HAE) Patients rhC1INH - Hereditary Angioedema | Phase 2 | Completed | Pharming Technologies B.V. | 57 | 2012-01-17 | 2024-03-29 |
| Efficacy, Safety and Immunogenicity Study of Recombinant Human C1 Inhibitor for the Treatment of Acute HAE Attacks rhC1INH, Placebo (Saline) - Hereditary Angioedema | Phase 3 | Completed | Pharming Technologies B.V. | 75 | 2011-01-01 | 2015-08-07 |
| Recombinant Human C1 Inhibitor for the Treatment of Acute Attacks in Patients With Hereditary Angioedema i.v. recombinant human C1 inhibitor - Genetic Disorders | Phase 2 / Phase 3 | Completed | Pharming Technologies B.V. | 14 | 2004-04-01 | 2013-02-22 |
Angioedemas, Hereditary (4) · Angioedema (2) · Delayed Graft Function (1) · Genetic Diseases, Inborn (1) · Renal Insufficiency (1)
Pharming Technologies B.V. (5) · University of Wisconsin, Madison (1)
United States (5) · Italy (3) · North Macedonia (3) · Romania (3) · Canada (2) · Czechia (2) · Hungary (2) · Israel (2) · Poland (2) · Serbia (2) · Bulgaria (1) · Germany (1) · Netherlands (1) · Slovakia (1) · South Africa (1)
Anurag Relan, MD (2) · Jan Nuijens, MD, PhD (1) · Luis Fernandez (1)