RG-1507 monoclonal antibody: Clinical Trials

6 terminated, 3 completed. 5 Phase 1, 4 Phase 2.

By phase and status

Phase	Trials	Status
Phase 1	5	Completed 3, Terminated 2
Phase 2	4	Terminated 4

Follow this drug Literature Review of RG-1507 monoclonal antibody trials Research Report on RG-1507 monoclonal antibody

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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
A Multiple Ascending Dose Study of the mTOR Inhibitor (RAD001) in Combination With R1507 in Patients With Advanced Solid Tumors RAD001, RG1507 - Neoplasms	Phase 1	Terminated	Hoffmann-La Roche	11	2009-11-01	2016-11-02
A Study to Evaluate the Biological Activity of R1507 in Women With Operable Breast Cancer RG1507 - Breast Cancer	Phase 1	Completed	Hoffmann-La Roche	8	2009-07-01	2016-11-02
A Study of R1507 in Combination With Multiple Standard Chemotherapy Treatments in Patients With Advanced Solid Tumors RG1507, RO1507, bevacizumab [Avastin] - Neoplasms	Phase 1	Terminated	Hoffmann-La Roche	104	2009-02-01	2016-11-02
A Study of R1507 in Combination With Letrozole in Postmenopausal Women With Advanced Breast Cancer RG1507, Letrozole - Breast Cancer	Phase 2	Terminated	Hoffmann-La Roche	6	2009-01-28	2020-11-13
A Study of the Effect of R1507 in Combination With Tarceva (Erlotinib) on Progression-Free Survival in Patients With Stage IIIb/IV Non-Small Cell Lung Cancer (NSCLC). Placebo, RG1507, erlotinib [Tarceva] - Non-Squamous Non-Small Cell Lung Cancer	Phase 2	Terminated	Hoffmann-La Roche	171	2008-11-10	2021-01-05
A Study of the Effect of R1507 in Combination With Tarceva (Erlotinib) on Progression-Free Survival in Patients With Stage IIIb/IV Non-Small Cell Lung Cancer (NSCLC) Having Received Tarceva Monotherapy. RG1507, erlotinib [Tarceva] - Non-Small Cell Lung Cancer	Phase 2	Terminated	Hoffmann-La Roche	35	2008-11-01	2013-06-24
A Study of R1507 in Participants With Recurrent or Refractory Sarcoma RG1507 - Sarcoma	Phase 2	Terminated	Hoffmann-La Roche	317	2007-12-18	2021-02-03
A Multiple Ascending Dose Study of R1507 in Children and Adolescents With Advanced Solid Tumors. RG1507 - Neoplasms	Phase 1	Completed	Hoffmann-La Roche	34	2007-12-01	2016-11-01
A Multiple Ascending Dose Study of R1507 in Patients With Advanced Solid Tumors. RG1507 - Neoplasms	Phase 1	Completed	Hoffmann-La Roche	98	2006-04-01	2016-11-02

Conditions studied

Neoplasms (4)  ·  Breast Neoplasms (2)  ·  Carcinoma, Non-Small-Cell Lung (1)  ·  Sarcoma (1)

Sponsors

Hoffmann-La Roche (9)

Countries

United States (8)  ·  Canada (3)  ·  France (3)  ·  Italy (3)  ·  United Kingdom (3)  ·  Australia (2)  ·  Germany (2)  ·  Poland (2)  ·  Spain (2)  ·  Belgium (1)  ·  Ireland (1)  ·  Netherlands (1)  ·  Norway (1)  ·  Sweden (1)

Results publications

PMID 22025149, PMID 22025157, PMID 22682017, PMID 33768488

NIH funding

2008 (4)