RFB4(dsFv)-PE38 recombinant immunotoxin: Clinical Trials

5 trials of RFB4(dsFv)-PE38 recombinant immunotoxin, newest first

ClinicalTrials Daily  ·  Areas  ·  Conditions  ·  Drugs  ·  Sponsors  ·  

2 completed, 1 suspended, 1 terminated, 1 withdrawn. 4 Phase 1, 1 Phase 2.

By phase and status

PhaseTrialsStatus
Phase 14Completed 2, Suspended 1, Withdrawn 1
Phase 21Terminated 1

Follow RFB4(dsFv)-PE38 recombinant immunotoxin: new trials by email Literature Review of RFB4(dsFv)-PE38 recombinant immunotoxin trials Research Report on RFB4(dsFv)-PE38 recombinant immunotoxin

Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Retreatment Protocol for BL22 Immunotherapy in Relapsed or Refractory Hairy Cell Leukemia
BL22 (CAT-3888) - Hairy Cell Leukemia
Phase 2TerminatedNational Cancer Institute (NCI)12009-02-012015-10-29
BL22 Immunotoxin in Treating Patients With Refractory Chronic Lymphocytic Leukemia, Prolymphocytic Leukemia, or Non-Hodgkin's Lymphoma
BL22 immunotoxin, antibody-drug conjugate therapy, immunotoxin therapy - Leukemia, Lymphoma
Phase 1CompletedMedImmune LLC242005-06-012010-06-22
BL22 Immunotoxin In Treating Young Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia or Non-Hodgkin's Lymphoma
BL22 immunotoxin, antibody-drug conjugate therapy, immunotoxin therapy - Leukemia, Lymphoma
Phase 1SuspendedMedImmune LLC952004-01-012007-12-28
Immunotoxin Therapy in Treating Patients With Hairy Cell Leukemia
BL22 immunotoxin - Leukemia
Phase 1CompletedNational Cancer Institute (NCI)1998-12-012015-04-29
BL22 Immunotoxin in Treating Patients With Non-Hodgkin's Lymphoma or Chronic Lymphocytic Leukemia
BL22 immunotoxin, antibody therapy, biological response modifier therapy - Leukemia, Lymphoma
Phase 1WithdrawnNational Cancer Institute (NCI)2015-04-28

Conditions studied

Leukemia (5)  ·  Lymphoma (3)  ·  Leukemia, Hairy Cell (2)  ·  Leukemia, Lymphocytic, Chronic, B-Cell (2)  ·  Leukemia, Prolymphocytic (2)  ·  Lymphoma, B-Cell, Marginal Zone (2)  ·  Lymphoma, Follicular (2)  ·  Lymphoma, Mantle-Cell (2)  ·  Lymphoma, Non-Hodgkin (2)  ·  Precursor Cell Lymphoblastic Leukemia-Lymphoma (2)  ·  Burkitt Lymphoma (1)  ·  Dendritic Cell Sarcoma, Interdigitating (1)  ·  Lymphoma, Large B-Cell, Diffuse (1)  ·  Lymphoma, Large-Cell, Immunoblastic (1)  ·  Waldenstrom Macroglobulinemia (1)

Sponsors

National Cancer Institute (NCI) (3)  ·  MedImmune LLC (2)

Countries

United States (5)

Top investigators

Robert Kreitman, MD (3)  ·  Alan S. Wayne, MD (1)  ·  Robert J Kreitman, M.D. (1)

Results publications

PMID 11474661, PMID 16061911