3 completed, 2 terminated. 2 Phase 1, 2 Phase 2, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 2 | Completed 1, Terminated 1 |
| Phase 2 | 2 | Completed 2 |
| Phase 3 | 2 | Completed 1, Terminated 1 |
Follow QPI-1002: new trials by email Literature Review of QPI-1002 trials Research Report on QPI-1002
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| QPI-1002 Phase 3 for Prevention of Major Adverse Kidney Events (MAKE) in Subjects at High Risk for AKI Following Cardiac Surgery teprasiran, Placebo - Cardiac Surgery | Phase 3 | Terminated | Quark Pharmaceuticals | 1043 | 2018-06-29 | 2021-07-16 |
| QPI-1002 for Prevention of Delayed Graft Function in Recipients of an Older Donor Kidney Transplant QPI-1002, Placebo - Delayed Graft Function | Phase 3 | Completed | Quark Pharmaceuticals | 594 | 2016-03-01 | 2020-05-13 |
| A Study to Evaluate Efficacy and Safety of QPI-1002 for Prevention of Acute Kidney Injury Following Cardiac Surgery QPI-1002, Placebo - Acute Kidney Injury | Phase 2 | Completed | Quark Pharmaceuticals | 341 | 2015-12-01 | 2019-01-10 |
| I5NP for Prophylaxis of Delayed Graft Function in Kidney Transplantation I5NP, Saline - Delayed Graft Function, Other Complication of Kidney Transplant | Phase 1 / Phase 2 | Completed | Quark Pharmaceuticals | 374 | 2008-12-01 | 2014-09-18 |
| A Dose Escalation and Safety Study of I5NP to Prevent Acute Kidney Injury (AKI) in Patients at High Risk of AKI Undergoing Major Cardiovascular Surgery (QRK.004) I5NP, Placebo - Acute Renal Failure, Acute Kidney Injury | Phase 1 | Terminated | Quark Pharmaceuticals | 3 | 2008-05-01 | 2010-11-16 |
Acute Kidney Injury (2) · Delayed Graft Function (2)
United States (5) · Canada (4) · Germany (4) · France (3) · Spain (3) · Australia (2) · Belgium (2) · Czechia (2) · Argentina (1) · Austria (1) · Brazil (1) · Netherlands (1) · New Zealand (1) · United Kingdom (1)
Elizabeth Squiers, M.D. (1) · John Holman, M.D.,Ph.D. (1) · Martin S. Polinsky, M.D. (1) · Nitsan Halevy, MD (1) · Shai Erlich, Ph.D. (1)