2 completed, 1 suspended. 2 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 2 | Completed 1, Suspended 1 |
| Phase 1 | 1 | Completed 1 |
Follow Pyronaridine Tetraphosphate: new trials by email Literature Review of Pyronaridine Tetraphosphate trials Research Report on Pyronaridine Tetraphosphate
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pyronaridine in Acute Myeloid Leukemia (AML) Pyronaridine Tetraphosphate - Acute Myeloid Leukemia (AML), Acute Lymphoblastic Leukemia (ALL) | Phase 2 | Suspended | Armaceutica, Inc. | 200 | 2028-02-21 | 2026-10-19 |
| Efficacy, Safety, and PK of M5717 in Combination With Pyronaridine as Chemoprevention in Adults and Adolescents With Asymptomatic Plasmodium Falciparum Infection (CAPTURE-2) M5717 60 mg, Pyronaridine, Atovaquone-Proguanil - Malaria Infection | Phase 2 | Completed | Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany | 192 | 2023-11-28 | 2026-02-06 |
| A Healthy Volunteer Safety Study of Pyronaridine Tetraphosphate Taken in Combination With Piperaquine Tetraphosphate Pyronaridine Tetraphosphate, Piperaquine tetraphosphate, Placebo - Healthy | Phase 1 | Completed | Medicines for Malaria Venture | 37 | 2022-02-14 | 2024-05-10 |
Asymptomatic Infections (1) · Leukemia (1) · Leukemia, Myeloid, Acute (1) · Malaria (1) · Malaria, Falciparum (1) · Neoplasms (1) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (1)
Armaceutica, Inc. (1) · Medicines for Malaria Venture (1) · Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany (1)
Burkina Faso (1) · Kenya (1) · Senegal (1) · The Gambia (1) · United Kingdom (1) · Zambia (1)
Renato J Aguilera, PhD (1) · Stephan Chalon, MD PhD (1) · Ulrike Lorch, MD (1)