5 completed. 5 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 5 | Completed 5 |
Follow Placebo for MAD: new trials by email Literature Review of Placebo for MAD trials Research Report on Placebo for MAD
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A First-in-Human SAD/MAD Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ENC1018 in Healthy Adult Subjects ENC1018 for SAD, Placebo for SAD, ENC1018 for MAD - Healthy | Phase 1 | Completed | EnnovaBio Australia Pharmaceuticals Pty Ltd | 72 | 2024-03-05 | 2025-04-25 |
| A First In Human (FIH) Study of IBI356 in Healthy Participants and in Atopic Dermatitis Patients IBI356 for MAD, Dupilumab for MAD, IBI356 for SAD - Healthy Participants, Atopic Dermatitis Patients | Phase 1 | Completed | Innovent Biologics (Suzhou) Co. Ltd. | 99 | 2024-01-05 | 2025-09-02 |
| Trichomylin® Safety, Tolerability & Pharmacokinetics in Healthy Adults and First in Human Osteoarthritis Pain Evaluation Trichomylin for SAD, Placebo for SAD, Trichomylin for MAD - Healthy, Osteoarthritis | Phase 1 | Completed | ZYUS Life Sciences Inc. | 41 | 2021-04-19 | 2024-06-27 |
| A Study of the Safety, Tolerability, and Pharmacokinetics of SPR720 in Healthy Volunteers SPR720 for SAD, Placebo for SAD, SPR720 for MAD - Healthy Volunteers | Phase 1 | Completed | Spero Therapeutics | 96 | 2018-12-18 | 2019-10-28 |
| SAD and MAD Study to Evaluate Safety, Tolerability, and Pharmacokinetics (PK) of TD-1473 in Healthy Subjects TD-1473 for SAD, Placebo for SAD, TD-1473 for MAD - Healthy | Phase 1 | Completed | Theravance Biopharma | 72 | 2015-12-01 | 2021-01-19 |
Chronic Pain (1) · Osteoarthritis (1)
EnnovaBio Australia Pharmaceuticals Pty Ltd (1) · Innovent Biologics (Suzhou) Co. Ltd. (1) · Spero Therapeutics (1) · Theravance Biopharma (1) · ZYUS Life Sciences Inc. (1)
Australia (2) · China (1) · United Kingdom (1) · United States (1)
Annelize Koch, MBChB (1) · Paul Wabnitz, Dr (1) · Philip Ryan, Doctor (1)