6 completed, 2 active not recruiting, 2 recruiting, 1 unknown. 6 Not applicable, 3 Phase 1, 2 Phase 3, 1 Early Phase 1, 1 Phase 2.
Follow Perflutren Lipid Microspheres: new trials by email Literature Review of Perflutren Lipid Microspheres trials Research Report on Perflutren Lipid Microspheres
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Ultrasound With Subharmonic Imaging and Subharmonic Aided Pressure Estimation (SHAPE) to Identify Portal Hypertension Electronic Health Record Review, Liver Biopsy, Medical Device Usage and Evaluation - Portal Hypertension | Not applicable | Recruiting | Mayo Clinic | 60 | 2025-03-13 | 2026-08-14 |
| Prostate Cancer Diagnosis by Multiparametric Ultrasound (Wholemount) Perflutren Lipid Microspheres, Ultrasound - Prostate Carcinoma | Phase 3 | Active not recruiting | Thomas Jefferson University | 70 | 2022-06-15 | 2025-09-04 |
| SHAPE Neoadjuvant Chemotherapy Response Contrast-Enhanced Ultrasound, Perflutren Lipid Microspheres, Ultrasound - Anatomic Stage III Breast Cancer AJCC v8, Locally Advanced Breast Carcinoma | Phase 2 / Phase 3 | Active not recruiting | Kibo Nam | 122 | 2021-04-19 | 2026-09-23 |
| Contrast Enhanced Ultrasound Medical Imaging for Identifying Breast Masses Contrast-Enhanced Ultrasound, Perflutren Lipid Microspheres, Sulfur Hexafluoride Lipid Microspheres - Breast Carcinoma | Phase 1 | Recruiting | University of Southern California | 100 | 2020-11-05 | 2026-02-02 |
| Contrast-Enhanced Ultrasound in Diagnosing Patients With Liver Cancer Undergoing Yttrium-90 Radioembolization Perflutren Lipid Microspheres, Sulfur Hexafluoride Lipid Microspheres, Dynamic Contrast-Enhanced Ultrasound Imaging - Hepatocellular Carcinoma | Not applicable | Withdrawn | University of Southern California | 2017-11-07 | 2019-05-16 | |
| Contrast-Enhanced Subharmonic Ultrasound Imaging in Improving Characterization of Adnexal Masses in Patients Undergoing Surgery Perflutren Lipid Microspheres, Contrast-Enhanced Subharmonic Ultrasound Imaging - Adnexal Mass | Early Phase 1 | Completed | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University | 12 | 2017-08-01 | 2025-05-15 |
| Feasibility 3D Perfusion Ultrasound for Liver Cancer SABR Planning and Response Evaluation perflutren lipid microspheres, 3D ultrasound - Liver Cancer, Liver Tumor | Not applicable | Completed | Stanford University | 11 | 2014-11-18 | 2023-07-11 |
| Subharmonic Imaging and Pressure Estimation for Monitoring Neoadjuvant Chemotherapy Definity infusion - Breast Cancer | Not applicable | Completed | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University | 17 | 2014-03-01 | 2025-05-06 |
| Contrast-Enhanced Ultrasound in Predicting Treatment Response in Patients With Liver Cancer Receiving Transarterial Chemoembolization With Drug Eluting Beads Perflutren Lipid Microspheres, Dynamic Contrast-Enhanced Ultrasound Imaging, Contrast-enhanced Magnetic Resonance Imaging - Hepatocellular Carcinoma | Phase 1 | Completed | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University | 15 | 2012-12-12 | 2025-05-02 |
| Contrast Sonography for Evaluation of Liver Tumors Prior to Radiofrequency Ablation perflutren lipid microspheres - Liver Neoplasms | Not applicable | Completed | University of California, Davis | 8 | 2007-04-01 | 2017-07-11 |
| Contrast-Enhanced Ultrasonography in Diagnosing Early-Stage Ovarian Cancer in Patients With an Adnexal Mass Undergoing Surgery to Remove the Ovary Definity, medical chart review - Ovarian Cancer | Phase 1 | Completed | Icahn School of Medicine at Mount Sinai | 67 | 2007-01-01 | 2017-04-18 |
| Assessment of Changes in Renal Cortical and Medullary Blood Flow by Contrast Ultrasound perflutren lipid microspheres - Kidney | Not applicable | Unknown | University of Virginia | 20 | 2006-06-01 | 2008-08-07 |
Carcinoma, Hepatocellular (3) · Breast Neoplasms (2) · Liver Neoplasms (2) · Carcinoma, Ovarian Epithelial (1) · Hypertension, Portal (1) · Ovarian Neoplasms (1) · Prostatic Neoplasms (1)
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University (3) · University of Southern California (2) · Icahn School of Medicine at Mount Sinai (1) · Kibo Nam (1) · Mayo Clinic (1) · Stanford University (1) · Thomas Jefferson University (1) · University of California, Davis (1) · University of Virginia (1)
United States (11) · Netherlands (1)
Flemming Forsberg, PhD (3) · Arthur C. Fleischer, MD (1) · Bino A Varghese, PhD (1) · Daniel T. Chang (1) · David Fishman, MD (1) · Harshawn Malhi, MD (1) · Jaydev K. Dave, PhD (1) · John P. McGahan, M.D. (1) · Kambiz Kalantarinia, MD (1) · Kibo Nam, MD (1)
P30CA014089 (2), P30CA068485 (1), R01CA252311 (1), R21CA190930 (1), R37CA234428 (1)