pamidronate disodium: Clinical Trials

6 trials of pamidronate disodium, newest first

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5 completed, 1 terminated. 2 Phase 1, 2 Phase 2, 1 Not applicable, 1 Phase 3.

By phase and status

PhaseTrialsStatus
Phase 12Completed 2
Phase 22Completed 2
Not applicable1Terminated 1
Phase 31Completed 1

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Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Efficacy of Bisphosphonates in Patients With Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis (SAPHO) Syndrome
pamidronate disodium - SAPHO Syndrome
Phase 1CompletedPeking Union Medical College Hospital302015-10-012016-10-13
The Use of Bisphosphonates in the Treatment of Avascular Necrosis of the Femoral Head
Pamidronate Disodium - Femoral Head Avascular Necrosis
Not applicableTerminatedThe Hospital for Sick Children202009-07-012017-10-13
Arsenic Trioxide and Pamidronate in Treating Patients With Advanced Solid Tumors or Multiple Myeloma
pamidronate disodium, arsenic trioxide, laboratory biomarker analysis - Refractory Multiple Myeloma, Unspecified Adult Solid Tumor, Protocol Specific
Phase 1CompletedNational Cancer Institute (NCI)242005-04-012013-01-07
Dexamethasone With or Without Thalidomide in Treating Patients With Newly Diagnosed Multiple Myeloma
dexamethasone, pamidronate disodium, thalidomide - Multiple Myeloma and Plasma Cell Neoplasm
Phase 3CompletedNational Cancer Institute (NCI)2002-04-012014-04-04
Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Women With Metastatic Breast Cancer
filgrastim, anastrozole, carboplatin - Breast Cancer
Phase 2CompletedHackensack Meridian Health1999-10-012013-05-30
Combination Chemo, Peripheral Stem Cell Transplant, Biological Therapy, Pamidronate and Thalidomide for Multiple Myeloma
filgrastim, recombinant interferon alfa, busulfan - Multiple Myeloma and Plasma Cell Neoplasm
Phase 2CompletedCity of Hope Medical Center771999-07-082026-11-03

Conditions studied

Multiple Myeloma (3)  ·  Neoplasms, Plasma Cell (2)  ·  Acquired Hyperostosis Syndrome (1)  ·  Breast Neoplasms (1)  ·  Femur Head Necrosis (1)  ·  Osteonecrosis (1)

Sponsors

National Cancer Institute (NCI) (2)  ·  City of Hope Medical Center (1)  ·  Hackensack Meridian Health (1)  ·  Peking Union Medical College Hospital (1)  ·  The Hospital for Sick Children (1)

Countries

United States (4)  ·  Canada (1)  ·  Puerto Rico (1)  ·  South Africa (1)

Top investigators

Andrew L. Pecora, MD, FACP (1)  ·  Chen Li, Master (1)  ·  George Somlo, MD (1)  ·  James Wright, MD (1)  ·  Przemyslaw Twardowski (1)  ·  S. V. Rajkumar, MD (1)

Results publications

PMID 16224404, PMID 16365178

NIH funding

P30CA033572 (1), U01CA062505 (1), U10CA021115 (1)