11 completed. 11 Phase 1.
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All 11 trials
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
Taste Assessment of Ozanimod Ozanimod - Healthy Volunteers | Phase 1 | Completed | 7 | 2021-09-09 | 2023-06-18 |
Study to Evaluate the Pressor Effect of Oral Tyramine During Ozanimod Treatment in Healthy Adult Participants Placebo, Rasigiline, Phenelzine - Healthy Volunteers | Phase 1 | Completed | 128 | 2021-07-19 | 2023-08-31 |
A Phase 1, Multicenter, Open-Label Study to Evaluate the Effect of Mild or Moderate Hepatic Impairment on the Multiple-Dose Pharmacokinetics of Ozanimod Ozanimod - Liver Diseases, Digestive System Diseases | Phase 1 | Completed | 26 | 2020-12-18 | 2022-06-14 |
A Study to Evaluate the Relative Bioavailability of a Pediatric Granule Formulation of Ozanimod in Healthy Adult Subjects Ozanimod - Healthy Volunteers | Phase 1 | Completed | 56 | 2020-10-07 | 2021-09-20 |
A Study to Evaluate the Pharmacokinetics of Single Oral Doses of Ozanimod in Healthy Adult Chinese Subjects Ozanimod - Healthy Volunteer | Phase 1 | Completed | 24 | 2020-08-12 | 2021-03-25 |
Drug Interaction Study of the Effect on Cyclosporine on Ozanimod and Major Active Metabolites Ozanimod, Cyclosporine - Healthy Volunteers | Phase 1 | Completed | 40 | 2019-10-04 | 2020-08-24 |
Drug-drug Interaction Study of Ozanimod With Tyramine to Evaluate the Effect on Pressor Response Phenelzine, Tyramine, Phenelzine placebo - Healthy Volunteer | Phase 1 | Completed | 92 | 2018-07-24 | 2019-07-19 |
Drug-drug Interaction Study of Ozanimod With Pseudoephedrine to Evaluate the Effect on Blood Pressure and Heart Rate ozanimod, Pseudoephedrine, ozanimod placebo - Healthy Volunteers | Phase 1 | Completed | 54 | 2018-07-11 | 2019-05-30 |
Drug-drug Interaction Study of Ozanimod With Inhibitor or Inducer of CYP2C8 and/or CYP3A Ozanimod, Gemfibrozil, Itraconazole - Healthy Volunteer | Phase 1 | Completed | 100 | 2018-06-20 | 2019-05-30 |
A Single Dose Oral Excretion Balance Study of [14C]-RPC1063 in Healthy Male Adults RPC1063 - Healthy Volunteers | Phase 1 | Completed | 6 | 2016-10-01 | 2017-01-27 |
Pharmacokinetics and Pharmacodynamics Study of RPC1063 in RMS RPC1063 - Multiple Sclerosis | Phase 1 | Completed | 22 | 2016-06-23 | 2018-03-27 |
Conditions studied
Digestive System Diseases (1) · Liver Diseases (1) · Lymphoma, Follicular (1) · Multiple Sclerosis (1)
Sponsors
Celgene (10) · Bristol-Myers Squibb (1)
Countries
United States (9) · China (1) · United Kingdom (1)
Top investigators
Jonathan Tran, Pharm.D (5) · Massimo Attanasio, MD (1) · Peijin Zhang, M.D, PhD (1)
Results publications
PMID 32737072, PMID 32857315, PMID 33025342