11 completed, 2 unknown, 1 terminated. 11 Not applicable, 1 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 11 | Completed 9, Terminated 1, Unknown 1 |
| Phase 2 | 1 | Completed 1 |
| Phase 4 | 1 | Completed 1 |
Follow oral appliance: new trials by email Literature Review of oral appliance trials Research Report on oral appliance
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Myofunctional Training for Obstructive Sleep Apnea Patients After Transoral Robotic Surgery transoral robotic surgery, oral appliance, using continuous positive airway pressure - Sleep Apnea, Obstructive | Not applicable | Completed | National Cheng-Kung University Hospital | 81 | 2020-01-01 | 2024-10-21 |
| The Effect of the DryMouth Shield on Snoring DryMouth Shield - Snoring | Not applicable | Terminated | VMS Medical Products, Inc | 3 | 2018-10-15 | 2022-04-27 |
| Long Term Oral Appliance Therapy Effectiveness for Obstructive Sleep Apnea Syndrome Oral Appliance - Obstructive Sleep Apnea | Unknown | University of British Columbia | 1000 | 2018-04-01 | 2024-01-23 | |
| Combined Upper-airway and Breathing Control Therapies for Obstructive Sleep Apnea Oral appliance, Oxygen, Oral appliance plus oxygen - Obstructive Sleep Apnea | Phase 2 | Completed | Brigham and Women's Hospital | 41 | 2017-09-06 | 2025-05-04 |
| Comparison of the Effectiveness of Three Different Treatment Methods in Myofascial Pain Patients NSAID, oral appliance, dry needling - Temporomandibular Disorder | Not applicable | Completed | Pomeranian Medical University Szczecin | 90 | 2016-07-01 | 2018-01-17 |
| Adherence and Preference of Continuous Positive Airway Pressure Versus Mandibular Advancement Splints in Obstructive Sleep Apnea Patients: A Randomized Trial Positive Airway Pressure (PAP), Mandibular Advancement Splints (MAS) - Obstructive Sleep Apnea | Not applicable | Completed | University of British Columbia | 79 | 2015-11-01 | 2022-11-30 |
| Characterizing Upper Airway Collapse to Guide Patient Selection for Oral Appliance Therapy for Obstructive Sleep Apnea Oral appliance, BluePro oral appliance - Sleep Apnea, Obstructive | Not applicable | Completed | Brigham and Women's Hospital | 25 | 2015-07-14 | 2022-03-09 |
| Comparative Efficacy Study of Titratable Versus Active Mandibular Advancement Splint in Sleep Apnea Somnyx ®, Narval ORM ® or SomnoDent ® - Obstructive Sleep Apnea | Not applicable | Completed | Université de Montréal | 100 | 2014-08-01 | 2024-03-29 |
| The Effects of Oral Appliance Therapy on Masseter Muscle Activity in Obstructive Sleep Apnea mandibular advancement appliance - Obstructive Sleep Apnea | Not applicable | Completed | Université de Montréal | 18 | 2014-02-01 | 2018-05-11 |
| Titration of Continuous Positive Airway Pressure Could Predict Success of Oral Appliance to Treat Sleep Apnea Oral appliance - Obstructive Sleep Apnea | Not applicable | Unknown | Associacao Fundo de Incentivo a Psicofarmcologia | 60 | 2010-10-01 | 2011-10-26 |
| Comparing the Effect of Physical Therapy With Oral Appliance on Temporomandibular Disorder Related Myofascial Pain PT program, oral appliance - Temporomandibular Disorder | Not applicable | Completed | National Taiwan University Hospital | 49 | 2010-06-01 | 2012-11-14 |
| Sleep Disordered Breathing and Gestational Hypertension CPAP, Oral Appliance - Sleep Disordered Breathing, Obstructive Sleep Apnea | Not applicable | Completed | University of Saskatchewan | 26 | 2008-12-01 | 2009-09-09 |
| Pharyngeal Size in Patients With Obstructive Tonsils Under Orthodontic Treatment Bioajusta X Orthodontic treatment - Sleep Apnea Syndrome, Malocclusion | Phase 4 | Completed | University of Sao Paulo General Hospital | 40 | 2006-11-01 | 2012-06-22 |
| Oral Appliance Therapy in Obstructive Sleep Apnea Mandibular Advancement Device (MAD), nasal CPAP, placebo - Obstructive Sleep Apnea | Not applicable | Completed | VU University of Amsterdam | 64 | 2003-10-01 | 2014-12-25 |
Sleep Apnea, Obstructive (10) · Sleep Apnea Syndromes (3) · Snoring (2) · Temporomandibular Joint Disorders (2) · Hypertension, Pregnancy-Induced (1) · Malocclusion (1) · Patient Compliance (1) · Pre-Eclampsia (1)
Brigham and Women's Hospital (2) · University of British Columbia (2) · Université de Montréal (2) · Associacao Fundo de Incentivo a Psicofarmcologia (1) · National Cheng-Kung University Hospital (1) · National Taiwan University Hospital (1) · Pomeranian Medical University Szczecin (1) · University of Sao Paulo General Hospital (1) · University of Saskatchewan (1) · VMS Medical Products, Inc (1) · VU University of Amsterdam (1)
Canada (5) · United States (3) · Taiwan (2) · Australia (1) · Brazil (1) · France (1) · Netherlands (1)
Nelly Huynh, PhD (2) · Bartosz Dalewski, DMD,PhD (1) · Bradley A Edwards, PhD (1) · David A Wellman, PhD (1) · Fernanda Almeida, DDS,Phd (1) · Fernanda R Almeida, DDS, MSc, PhD (1) · Ghizlane Aarab, DDS (1) · John K Reid, MD (1) · Lia Rita A Bittencourt, MD, PhD (1) · Renata C Di Francesco, Phd (1) · Scott A Sands, PhD (1) · Walter R Nunes Jr., Ms (1)
PMID 16011634, PMID 18957843, PMID 19536571, PMID 20962502, PMID 21454959, PMID 21463349, PMID 32501212, PMID 33745505, PMID 35212262, PMID 35484327, PMID 39688178
R01HL128658 (1)