4 completed, 2 terminated. 6 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Completed 4, Terminated 2 |
Follow navarixin: new trials by email Literature Review of navarixin trials Research Report on navarixin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety Study of Navarixin (MK-7123) in Combination With Pembrolizumab (MK-3475) in Adults With Selected Advanced/Metastatic Solid Tumors (MK-7123-034) Navarixin, Pembrolizumab - Solid Tumors, Non-small Cell Lung Cancer | Phase 2 | Completed | Merck Sharp & Dohme LLC | 107 | 2018-04-10 | 2024-08-28 |
| Long-Term Study of the Effects of Navarixin (SCH 527123, MK-7123) in Participants With Moderate to Severe COPD (MK-7123-019) Navarixin, Placebo, Rescue medication - COPD | Phase 2 | Terminated | Merck Sharp & Dohme LLC | 616 | 2009-10-01 | 2019-01-02 |
| Efficacy and Safety of Navarixin (SCH 527123) in Participants With Allergen-Induced Asthma (P05363) Navarixin, Placebo - Asthma | Phase 2 | Completed | Merck Sharp & Dohme LLC | 19 | 2008-06-01 | 2019-01-02 |
| Neutrophilic Asthma Study With Navarixin (MK-7123, SCH 527123) (MK-7123-017)(COMPLETED) Navarixin, Placebo, Rescue medication - Neutrophilic Asthma | Phase 2 | Completed | Merck Sharp & Dohme LLC | 37 | 2008-05-01 | 2019-01-02 |
| A Study to Assess the Clinical Effects of Navarixin in Participants With Psoriasis (MK-7123-009) Navarixin 10 mg, Placebo - Psoriasis | Phase 2 | Completed | Merck Sharp & Dohme LLC | 31 | 2007-06-01 | 2019-02-05 |
| Study to Evaluate the Safety and Dose-Range of Navarixin (SCH 527123, MK-7123) in Participants With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) (MK-7123-012) Navarixin 1 mg, Navarixin 10 mg, Placebo to match navarixin - Chronic Obstructive Pulmonary Disease | Phase 2 | Terminated | Merck Sharp & Dohme LLC | 99 | 2006-12-01 | 2019-01-02 |
Pulmonary Disease, Chronic Obstructive (2) · Asthma (1) · Carcinoma, Non-Small-Cell Lung (1) · Psoriasis (1)
Australia (1) · Canada (1) · Israel (1) · South Korea (1) · United States (1)
PMID 22702508, PMID 25695403, PMID 38324085, PMID 40318595
2005 (1), 2008 (1)