2 recruiting, 1 enrolling by invitation. 3 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 3 | Recruiting 2, Enrolling by invitation 1 |
Follow LOT-CRT: new trials by email Literature Review of LOT-CRT trials Research Report on LOT-CRT
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Advancing Clinical Heart Failure Outcomes Leveraging Defibrillation Lead Implant System for Left Bundle Branch Area Pacing LBBAP Therapy, LOT-CRT, ICD - Heart Failure, Systolic Bundle Branch Block, Left | Not applicable | Recruiting | Medtronic Cardiac Rhythm and Heart Failure | 110 | 2026-10-13 | 2026-10-20 |
| LBBP + CSP Versus LBBP Alone for Cardiac Resynchronization Therapy Left Bundle Branch Optimized CRT, Stimulation of the left bundle branch area (LBBAP) - Heart Failure Low Output | Not applicable | Enrolling by invitation | Clinica Cardio VID | 10 | 2026-06-09 | 2026-07-23 |
| Comparing Three Types of Specialist Pacemakers to Improve Heart Function and Reduce Rhythm Problems in Heart Failure Biventricular pacing, Conduction system pacing, Left bundle optimised cardiac resynchronisation therapy - Heart Failure and Reduced Ejection Fraction, Dyssynchrony | Not applicable | Recruiting | Imperial College London | 60 | 2025-11-12 | 2026-02-24 |
Heart Failure (3) · Heart Failure, Systolic (1)
Clinica Cardio VID (1) · Imperial College London (1) · Medtronic Cardiac Rhythm and Heart Failure (1)
Colombia (1) · United Kingdom (1) · United States (1)
Ahran D Arnold, MBBS, BSc, MSc, MRCP, PhD (1) · Juan F Agudelo, Electrophysiologist (1) · Susana Rios, Medical Epidemiologist (1) · Zachary I Whinnett, MBBS, BMedSci, MRCP, PhD (1)