itepekimab: Clinical Trials

5 trials of itepekimab, newest first

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5 completed. 5 Phase 2.

By phase and status

PhaseTrialsStatus
Phase 25Completed 5

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Trials (filtered) newest first · largest first

All 5 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
A Proof-of-Concept Study to Assess the Efficacy, Safety and Tolerability of Itepekimab (Anti--IL-33 mAb) in Participants With Chronic Rhinosinusitis Without Nasal Polyps
Itepekimab (SAR440340), Placebo, Mometasone furoate nasal spray (MFNS) - Chronic Rhinosinusitis Without Nasal Polyps
Phase 2CompletedSanofi662024-12-162026-08-25
A Proof-of-Concept Study to Assess the Efficacy, Safety and Tolerability of Itepekimab (Anti-IL-33 mAb) in Participants With Non-cystic Fibrosis Bronchiectasis
Itepekimab (SAR440340), Placebo - Bronchiectasis
Phase 2CompletedSanofi3142024-02-202026-10-07
Mechanistic Study of the Effect of Itepekimab on Airway Inflammation in Patients With COPD
Itepekimab SAR440340 - Chronic Obstructive Pulmonary Disease
Phase 2CompletedSanofi492022-05-192026-08-31
Proof-of-Concept Study to Assess the Efficacy, Safety and Tolerability of SAR440340 (Anti-IL-33 mAb) in Patients With Moderate-to-severe Chronic Obstructive Pulmonary Disease (COPD)
SAR440340, Placebo, Any Inhaled Corticosteroids as prescribed by treating physician as standard of care - Chronic Obstructive Pulmonary Disease
Phase 2CompletedSanofi3432018-07-162022-11-22
Evaluation of SAR440340 and as Combination Therapy With Dupilumab in Moderate-to-Severe Asthma Participants
SAR440340, Dupilumab, Fluticasone or Fluticasone/salmeterol combination - Asthma
Phase 2CompletedSanofi2962018-03-122022-06-14

Conditions studied

Pulmonary Disease, Chronic Obstructive (2)  ·  Asthma (1)  ·  Bronchiectasis (1)

Sponsors

Sanofi (5)

Countries

United States (5)  ·  Argentina (4)  ·  Chile (4)  ·  Poland (4)  ·  Canada (3)  ·  Germany (3)  ·  Turkey (Türkiye) (3)  ·  Belgium (2)  ·  Brazil (2)  ·  China (2)  ·  Denmark (2)  ·  France (2)  ·  Italy (2)  ·  Netherlands (2)  ·  Russia (2)

Results publications

PMID 34302758, PMID 34706171, PMID 36253275

NIH funding

2017 (2), 2023 (1)