5 completed. 5 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Completed 5 |
Follow itepekimab: new trials by email Literature Review of itepekimab trials Research Report on itepekimab
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Proof-of-Concept Study to Assess the Efficacy, Safety and Tolerability of Itepekimab (Anti--IL-33 mAb) in Participants With Chronic Rhinosinusitis Without Nasal Polyps Itepekimab (SAR440340), Placebo, Mometasone furoate nasal spray (MFNS) - Chronic Rhinosinusitis Without Nasal Polyps | Phase 2 | Completed | Sanofi | 66 | 2024-12-16 | 2026-08-25 |
| A Proof-of-Concept Study to Assess the Efficacy, Safety and Tolerability of Itepekimab (Anti-IL-33 mAb) in Participants With Non-cystic Fibrosis Bronchiectasis Itepekimab (SAR440340), Placebo - Bronchiectasis | Phase 2 | Completed | Sanofi | 314 | 2024-02-20 | 2026-10-07 |
| Mechanistic Study of the Effect of Itepekimab on Airway Inflammation in Patients With COPD Itepekimab SAR440340 - Chronic Obstructive Pulmonary Disease | Phase 2 | Completed | Sanofi | 49 | 2022-05-19 | 2026-08-31 |
| Proof-of-Concept Study to Assess the Efficacy, Safety and Tolerability of SAR440340 (Anti-IL-33 mAb) in Patients With Moderate-to-severe Chronic Obstructive Pulmonary Disease (COPD) SAR440340, Placebo, Any Inhaled Corticosteroids as prescribed by treating physician as standard of care - Chronic Obstructive Pulmonary Disease | Phase 2 | Completed | Sanofi | 343 | 2018-07-16 | 2022-11-22 |
| Evaluation of SAR440340 and as Combination Therapy With Dupilumab in Moderate-to-Severe Asthma Participants SAR440340, Dupilumab, Fluticasone or Fluticasone/salmeterol combination - Asthma | Phase 2 | Completed | Sanofi | 296 | 2018-03-12 | 2022-06-14 |
Pulmonary Disease, Chronic Obstructive (2) · Asthma (1) · Bronchiectasis (1)
Sanofi (5)
United States (5) · Argentina (4) · Chile (4) · Poland (4) · Canada (3) · Germany (3) · Turkey (Türkiye) (3) · Belgium (2) · Brazil (2) · China (2) · Denmark (2) · France (2) · Italy (2) · Netherlands (2) · Russia (2)
PMID 34302758, PMID 34706171, PMID 36253275
2017 (2), 2023 (1)