itepekimab: Clinical Trials

7 trials of itepekimab, newest first

ClinicalTrials Daily  ·  Areas  ·  Conditions  ·  Drugs  ·  Sponsors  ·  

5 completed, 2 terminated. 7 Phase 2.

By phase and status

PhaseTrialsStatus
Phase 27Completed 5, Terminated 2

Follow itepekimab: new trials by email Literature Review of itepekimab trials Research Report on itepekimab

Trials (filtered) newest first · largest first

All 7 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
A Proof-of-Concept Study to Assess the Efficacy, Safety and Tolerability of Itepekimab (Anti--IL-33 mAb) in Participants With Chronic Rhinosinusitis Without Nasal Polyps
Itepekimab (SAR440340), Placebo, Mometasone furoate nasal spray (MFNS) - Chronic Rhinosinusitis Without Nasal Polyps
Phase 2CompletedSanofi662024-12-162026-08-25
A Proof-of-Concept Study to Assess the Efficacy, Safety and Tolerability of Itepekimab (Anti-IL-33 mAb) in Participants With Non-cystic Fibrosis Bronchiectasis
Itepekimab (SAR440340), Placebo - Bronchiectasis
Phase 2CompletedSanofi3142024-02-202026-10-07
Mechanistic Study of the Effect of Itepekimab on Airway Inflammation in Patients With COPD
Itepekimab SAR440340 - Chronic Obstructive Pulmonary Disease
Phase 2CompletedSanofi492022-05-192026-08-31
Efficacy, Safety, and Pharmacokinetic Profiles of REGN3500 Administered to Adult Patients With Moderate-to-Severe Atopic Dermatitis
REGN3500, REGN3500-Matching Placebo - Atopic Dermatitis
Phase 2TerminatedRegeneron Pharmaceuticals1292018-11-132022-06-10
Efficacy and Safety of REGN3500 Monotherapy and Combination of REGN3500 Plus Dupilumab in Adult Patients With Moderate-to-Severe Atopic Dermatitis
REGN3500, Dupilumab, REGN3500 + Dupilumab Combo - Atopic Dermatitis
Phase 2TerminatedRegeneron Pharmaceuticals2062018-11-122021-11-01
Proof-of-Concept Study to Assess the Efficacy, Safety and Tolerability of SAR440340 (Anti-IL-33 mAb) in Patients With Moderate-to-severe Chronic Obstructive Pulmonary Disease (COPD)
SAR440340, Placebo, Any Inhaled Corticosteroids as prescribed by treating physician as standard of care - Chronic Obstructive Pulmonary Disease
Phase 2CompletedSanofi3432018-07-162022-11-22
Evaluation of SAR440340 and as Combination Therapy With Dupilumab in Moderate-to-Severe Asthma Participants
SAR440340, Dupilumab, Fluticasone or Fluticasone/salmeterol combination - Asthma
Phase 2CompletedSanofi2962018-03-122022-06-14

Conditions studied

Dermatitis, Atopic (2)  ·  Lymphoma, Follicular (2)  ·  Pulmonary Disease, Chronic Obstructive (2)  ·  Asthma (1)  ·  Bronchiectasis (1)

Sponsors

Sanofi (5)  ·  Regeneron Pharmaceuticals (2)

Countries

United States (7)  ·  Poland (6)  ·  Germany (5)  ·  Argentina (4)  ·  Canada (4)  ·  Chile (4)  ·  Spain (4)  ·  Belgium (3)  ·  Czechia (3)  ·  South Korea (3)  ·  Turkey (Türkiye) (3)  ·  United Kingdom (3)  ·  Australia (2)  ·  Brazil (2)  ·  China (2)

Results publications

PMID 39077906, PMID 34302758, PMID 34706171, PMID 36253275

NIH funding

2017 (2), 2018 (2), 2023 (1)