47 completed, 4 recruiting, 1 terminated. 52 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 52 | Completed 47, Recruiting 4, Terminated 1 |
Follow insulin degludec: new trials by email Literature Review of insulin degludec trials Research Report on insulin degludec
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Phase I Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Subcutaneous UBT38006 Injection in Healthy Adult Males UBT38006, Placebo, Insulin Degludec Injection - Type 2 Diabetes Mellitus (T2DM) | Phase 1 | Recruiting | The United Bio-Technology (Hengqin) Co., Ltd. | 53 | 2026-06-17 | 2026-09-15 |
| Single-ascending Dose Study of HEC-151 Injection HEC-151 Injection, Degludec insulin, Placebo - Healthy Adult Male | Phase 1 | Recruiting | Sunshine Lake Pharma Co., Ltd. | 81 | 2026-02-24 | 2026-09-25 |
| Comparison Study of Insulin GZR4 With Insulin Degludec GZR4 injection - Type 2 Diabetes | Phase 1 | Recruiting | Gan and Lee Pharmaceuticals, USA | 14 | 2025-08-15 | 2025-08-28 |
| A Clinical Study to Evaluate the Pharmacokinetic and Pharmacodynamics Properties of of SHR-3167 in Subjects With Type 2 Diabetes SHR-3167 Injection, Insulin Degludec Injection - Type 2 Diabetes | Phase 1 | Recruiting | Jiangsu HengRui Medicine Co., Ltd. | 55 | 2025-08-11 | 2026-04-17 |
| A Research Study of a New Medicine NNC0363-1063 in Healthy Participants and Participants With Type 1 Diabetes NNC0363-1063, Placebo, Insulin degludec - Diabetes Mellitus, Type 1 | Phase 1 | Completed | Novo Nordisk A/S | 117 | 2024-11-12 | 2026-04-09 |
| A Study of LY3938577 in Healthy Participants and Participants With Type 1 Diabetes Mellitus (T1DM) LY3938577, Placebo, Insulin Degludec - Healthy, Type 1 Diabetes Mellitus | Phase 1 | Completed | Eli Lilly and Company | 121 | 2024-05-15 | 2026-10-06 |
| A Study to Test How a New Long-acting Insulin Works in the Body of Patients With Type 2 Diabetes During Exercise and Prolonged Fasting Insulin icodec, Insulin degludec - Diabetes Mellitus, Type 2 | Phase 1 | Completed | Novo Nordisk A/S | 30 | 2024-02-26 | 2026-06-08 |
| A Study to Investigate the Safety and Tolerability of LY3938577 in Healthy Participants and Participants With Type 2 Diabetes Mellitus LY3938577, Placebo, Insulin degludec - Healthy, Type 2 Diabetes Mellitus | Phase 1 | Completed | Eli Lilly and Company | 66 | 2023-11-17 | 2024-07-24 |
| A Trial Investigating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GZR4 in Subjects With Type 2 Diabetes GZR4, Insulin Degludec - Diabetes | Phase 1 | Completed | Gan and Lee Pharmaceuticals, USA | 36 | 2023-03-22 | 2024-08-14 |
| A Clinical Study of GZR33 and GZR101 in Healthy Subjects GZR33 Injection, GZR101 Injection, Placebo - Healthy Subjects | Phase 1 | Completed | Gan and Lee Pharmaceuticals, USA | 28 | 2022-12-17 | 2024-08-16 |
| A Clinical Study Comparing the Pharmacokinetics and Pharmacodynamic Characteristics of Insulin Degludec Injection (RD15003) and Insulin Degludec Injection (Tresiba®) in Healthy Subjects Insulin degludec injection, RD15003, Insulin degludec, Tresiba - Type 2 Diabetes | Phase 1 | Completed | Sunshine Lake Pharma Co., Ltd. | 46 | 2021-10-08 | 2022-10-12 |
| A Study to Look at the Safety of NNC0363-0845 in Healthy People and People With Type 1 Diabetes NNC0363-0845, Placebo (NNC0363-0845), Insulin degludec - Healthy Volunteers, Diabetes Mellitus, Type 1 | Phase 1 | Completed | Novo Nordisk A/S | 68 | 2020-09-30 | 2023-06-27 |
| A Study of LY3209590 in Japanese Participants With Type 2 Diabetes Mellitus LY3209590, Insulin Degludec - Diabetes Mellitus, Type 2 | Phase 1 | Completed | Eli Lilly and Company | 28 | 2020-02-28 | 2020-12-03 |
| A Study of LY3374849 in Healthy Participants LY3374849 - SC, Insulin Degludec - SC, LY3374849 - IV - Healthy | Phase 1 | Completed | Eli Lilly and Company | 89 | 2018-11-20 | 2019-10-17 |
| A Trial to Investigate the Single Dose Pharmacokinetics of Insulin Degludec/Liraglutide Compared With Insulin Degludec and Liraglutide in Healthy Chinese Subjects insulin degludec/liraglutide, insulin degludec, liraglutide - Diabetes, Diabetes Mellitus, Type 2 | Phase 1 | Completed | Novo Nordisk A/S | 24 | 2017-09-29 | 2019-11-18 |
| A Trial Investigating the Safety, Tolerability, Pharmacokinetics (the Exposure of the Trial Drug in the Body) and Pharmacodynamics (the Effect of the Investigated Drug on the Body) of Insulin 287 in Subjects With Type 2 Diabetes Insulin icodec, placebo, insulin degludec - Diabetes, Diabetes Mellitus, Type 2 | Phase 1 | Completed | Novo Nordisk A/S | 50 | 2016-11-15 | 2021-08-27 |
| Comparing Pharmacodynamic and Pharmacokinetic Properties of Insulin Degludec and Insulin Glargine 300 U/mL at Steady-state Conditions in Subjects With Type 1 Diabetes Mellitus insulin degludec, insulin glargine - Diabetes, Diabetes Mellitus, Type 1 | Phase 1 | Completed | Novo Nordisk A/S | 60 | 2015-08-31 | 2019-05-01 |
| A Trial Investigating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Subcutaneously Administered NNC0148-0287 (Insulin 287) in Subjects With Type 2 Diabetes Insulin icodec, insulin degludec, placebo - Diabetes, Type 2 Diabetes Mellitus | Phase 1 | Completed | Novo Nordisk A/S | 49 | 2014-05-26 | 2021-03-08 |
| A Trial Investigating the Pharmacodynamic and Pharmacokinetic Properties of Insulin Degludec/Insulin Aspart 15 in Subjects With Type 1 Diabetes insulin degludec/insulin aspart 15, insulin degludec/insulin aspart, insulin degludec - Diabetes, Diabetes Mellitus, Type 1 | Phase 1 | Completed | Novo Nordisk A/S | 33 | 2013-01-01 | 2015-03-05 |
| A Trial Comparing the Effect of Exercise on Blood Glucose in Subjects With Type 1 Diabetes, Who Are Treated With Either Insulin Degludec or Insulin Glargine insulin degludec, insulin glargine - Diabetes, Diabetes Mellitus, Type 1 | Phase 1 | Completed | Novo Nordisk A/S | 40 | 2012-10-01 | 2016-12-16 |
Showing 20 of 52. Sign in to see all of them.
Diabetes Mellitus (39) · Diabetes Mellitus, Type 1 (23) · Diabetes Mellitus, Type 2 (16)
Novo Nordisk A/S (41) · Eli Lilly and Company (4) · Gan and Lee Pharmaceuticals, USA (3) · Sunshine Lake Pharma Co., Ltd. (2) · Jiangsu HengRui Medicine Co., Ltd. (1) · The United Bio-Technology (Hengqin) Co., Ltd. (1)
Germany (30) · China (8) · Austria (5) · Japan (3) · United States (3) · Hungary (1) · Singapore (1) · Slovakia (1)
PMID 25581159, PMID 28946756, PMID 22594461, PMID 22726241, PMID 23749405, PMID 24057153, PMID 24163264, PMID 24263619, PMID 24277680, PMID 24467565, PMID 24508419, PMID 24888255, PMID 25124362, PMID 25998481, PMID 26086190, PMID 26450456, PMID 27042281, PMID 28295934, PMID 29201153, PMID 33184152, PMID 33315813, PMID 34413118, PMID 39928225, PMID 42387301
2009 (8), 2008 (6), 2023 (2), 2005 (1), 2014 (1), 2016 (1), 2019 (1)