12 unknown. 12 Phase 2, 2 Phase 3, 1 Phase 1.
By phase and status
Follow IFL protocol: new trials by email Literature Review of IFL protocol trials Research Report on IFL protocol
Trials (filtered) newest first · largest first
All 12 trials
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
A Study of Ametumumab in Combination With Anti-PD-1 Monoclonal Antibody and FOLFIRI in Patients With RAS Wild-type Advanced Colorectal Cancer Ametumumab, Anti-PD-1 monoclonal antibody, Cetuximab - Colorectal Cancer | Phase 2 | Unknown | 84 | 2023-01-01 | 2023-02-01 |
The Efficacy and Safety of Fruquintinib Plus FOLFIRI/FOLFOX as Second-line Treatment in Patients With RAS-mutant Metastatic Colorectal Cancer Fruquintinib, FOLFIRI, mFOLFOX6 - Metastatic Colorectal Cancer | Phase 2 | Unknown | 68 | 2022-12-01 | 2022-12-02 |
Cetuximab Maintenance Treatment Versus Continuation After Induction Therapy in mCRC Cetuximab, mFOLFOX6, FOLFIRI - Colorectal Cancer | Phase 2 / Phase 3 | Unknown | 200 | 2021-11-01 | 2021-04-30 |
Post-surgical Liquid Biopsy-guided Treatment of Stage III and High-risk Stage II Colon Cancer Patients: the PEGASUS Trial CAPOX, Capecitabine, FOLFIRI - Colon Cancer | Phase 2 | Unknown | 140 | 2020-06-16 | 2023-09-28 |
Re-challenge Therapy With Chemotherapy & Panitumumab in Metastatic Colorectal Cancer Patients Treated With an Anti-EGFR Panitumumab - Metastatic Colorectal Cancer | Phase 2 | Unknown | 30 | 2020-06-10 | 2022-04-06 |
A Phase 2 Trial of SCO-101 in Combination With FOLFIRI for Patients With Metastatic Colorectal Cancer (mCRC) With Acquired Resistance to FOLFIRI FOLFIRI Protocol, SCO-101 - Metastatic Colorectal Cancer | Phase 1 / Phase 2 | Unknown | 35 | 2020-05-14 | 2022-03-02 |
Treatment With Hepatic Arterial Infusion of Oxaliplatin in Combination With Systemic FOLFIRI Chemotherapy and Bevacuzimab in Patients With Liver-only Colorectal Liver Metastases (CRLM): Conversion to Complete Resection in Patients With Initially Inoperable Liver-only CRLM. oxaliplatin, FOLFIRI Protocol, Bevacizumab - Liver Metastasis Colon Cancer | Phase 2 | Unknown | 49 | 2020-01-01 | 2020-10-20 |
Clinical Trial Evaluating FOLFIRI + Durvalumab vs FOLFIRI + Durvalumab and Tremelimumab in Second-line Treatment of Patients With Advanced Gastric or Gastro-oesophageal Junction Adenocarcinoma Durvalumab, Tremelimumab, FOLFIRI Protocol - Gastric Adenocarcinoma, Gastric Cancer | Phase 2 | Unknown | 107 | 2019-07-17 | 2024-07-08 |
Study to Evaluate the Efficiency of FOLFIRI as Seconde-line Chemotherapy in Neuroendocrine Carcinoma FOLFIRI Protocol - Neuroendocrine Carcinoma | Phase 2 | Unknown | 45 | 2017-05-02 | 2017-06-01 |
Cetuximab Monotherapy Maintenance Treatment in mCRC Cetuximab, mFOLFOX6, FOLFIRI - Colorectal Cancer | Phase 2 / Phase 3 | Unknown | 500 | 2016-11-01 | 2016-11-30 |
wXELIRI Versus FOLFIRI Regimen in the Treatment of Advanced Colorectal Cancer Patients wXELIRI regimen, FOLFIRI regimen - Colorectal Cancer | Phase 2 | Unknown | 100 | 2012-05-01 | 2012-11-29 |
Sorafenib and FOLFIRI Regimen in 2nd Colorectal Cancer (CRC) After Failure of Oxaliplatin Treatment sorafenib, FOLFIRI - Colorectal Neoplasms | Phase 2 | Unknown | 43 | 2008-11-01 | 2010-09-15 |
Conditions studied
Colorectal Neoplasms (9) · Carcinoma, Neuroendocrine (1) · Colonic Neoplasms (1) · Neoplasm Metastasis (1) · Neoplasms (1) · Stomach Neoplasms (1)
Sponsors
Fudan University (3) · Ruijin Hospital (2) · Federation Francophone de Cancerologie Digestive (1) · IFOM ETS - The AIRC Institute of Molecular Oncology (1) · King Abdullah Medical City (1) · Peking University (1) · Rabin Medical Center (1) · Scandion Oncology A/S (1) · Shanghai Celfuture Biotech Co., Ltd. (1)
Countries
China (5) · Spain (2) · Denmark (1) · France (1) · Germany (1) · Israel (1) · Italy (1) · Saudi Arabia (1)
Top investigators
Jacob Hagen Vasehus Schou, MD (1) · Jin Li, MD (1) · Jin Lin, PhD, MD (1) · Jun Zhang, MD & Ph.D (1) · Sara Lonardi, MD (1) · Shereef A Elsamany, MD (1) · Yifeng Wang, MD (1)
Results publications
PMID 38573643, PMID 40275077, PMID 42736431
NIH funding
2018 (1), 2019 (1)