3 terminated, 2 completed, 1 active not recruiting. 4 Phase 2, 2 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Completed 2, Terminated 2 |
| Phase 1 | 2 | Active not recruiting 1, Terminated 1 |
| Phase 3 | 1 | Terminated 1 |
Follow HiDAC: new trials by email Literature Review of HiDAC trials Research Report on HiDAC
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of Revumenib in Combination With Intensive Chemotherapy in Participants With Acute Myeloid Leukemias Revumenib, Chemotherapy Regimen, HiDAC - Acute Myeloid Leukemias | Phase 1 | Active not recruiting | Syndax Pharmaceuticals | 96 | 2024-05-21 | 2026-09-16 |
| Ficlatuzumab With High Dose Cytarabine in Relapsed and Refractory AML Ficlatuzumab, Cytarabine - Acute Myeloid Leukemia, Relapsed Acute Myeloid Leukemia | Phase 1 | Terminated | C. Babis Andreadis | 17 | 2015-05-01 | 2020-03-24 |
| Consolidation Therapy for Acute Myeloid Leukemia Guided by Leukemia Stem Cell Behavior Cytarabine consolidation, Allogeneic transplant - Acute Myeloid Leukemia | Phase 2 / Phase 3 | Terminated | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 10 | 2013-12-01 | 2018-08-14 |
| Treatment of PTCL With Aggressive Induction Therapy Followed by Autologous SCT Using Denileukin Diftitox (Ontak) Gemcitabine, Navelbine, Doxorubicin Hydrochloride Liposome Injection - Peripheral T-Cell Lymphoma | Phase 2 | Terminated | University of California, San Francisco | 21 | 2008-07-01 | 2020-04-27 |
| Study of CEP-701 (Lestaurtinib) in Patients With Acute Myeloid Leukemia (AML) CEP-701, high-dose cytarabine, Mitozantrone, Etoposide, Cytarabine (combination Chemotherapy) - Acute Myeloid Leukemia | Phase 2 | Completed | Cephalon | 224 | 2003-10-01 | 2016-07-21 |
| High-dose Cytarabine/Mitoxantrone Followed by Autotransplantation for t-MDS/t-AML Ara-C, Mitoxantrone, Etoposide - Myelodysplastic Syndrome, Acute Myeloid Leukemia | Phase 2 | Completed | University of Chicago | 32 | 2002-12-01 | 2014-02-11 |
Leukemia, Myeloid, Acute (5) · Lymphoma, T-Cell, Peripheral (1) · Myelodysplastic Syndromes (1)
C. Babis Andreadis (1) · Cephalon (1) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (1) · Syndax Pharmaceuticals (1) · University of California, San Francisco (1) · University of Chicago (1)
United States (6) · Australia (2) · Canada (2) · Spain (2) · Germany (1) · Israel (1) · Italy (1) · Netherlands (1) · New Zealand (1) · Poland (1) · Romania (1) · Russia (1) · Sweden (1) · Ukraine (1) · United Kingdom (1)
Charalambos Andreadis, MD (1) · Lawrence Kaplan, MD (1) · Lucy Godley, M.D. (1) · Margaret Showel, MD (1)