11 unknown, 6 completed, 5 not yet recruiting, 5 recruiting. 18 Phase 2, 6 Phase 3, 2 Not applicable, 2 Phase 1, 2 Phase 4.
Follow hetrombopag: new trials by email Literature Review of hetrombopag trials Research Report on hetrombopag
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Clinical Study on Prophylactic RespOnse To hEtrombopag for Secondary Prevention in Anti-Cancer Therapy-induced Thrombocytopeniae Continuous Hetrombopag for 2 Cycles, Cyclic 14-day Hetrombopag for 2 Cycles - Breast Cancer Patients at High Risk of Chemotherapy-induced Thrombocytopenia (CTIT) | Phase 2 | Recruiting | Fudan University | 126 | 2026-07-16 | 2026-11-02 |
| TPO-RA Plus Baricitinib vs. TPO-RA for ITP Baricitinib, TPO-RA - ITP - Immune Thrombocytopenia | Phase 2 | Not yet recruiting | Peking University People's Hospital | 100 | 2026-07-01 | 2026-06-25 |
| A Clinical Study on the Efficacy and Safety of Hetrombopag in the Treatment of Thrombocytopenia Induced by Gynecological Tumor Therapy hetrombopag 7.5 mg orally once daily - Chemotherapy Induced Thrombocytopenia | Phase 2 | Not yet recruiting | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 244 | 2026-04-15 | 2026-02-13 |
| CsA+EPAG/HPAG+Romiplostim N01 in Newly-diagnosed SAA/TD-NSAA Cyclosporine (CsA), thrombopoietin receptor agonist (TPO-RA), Romiplostim N01 - Severe Aplastic Anemia (SAA), Transfusion-dependent Non-severe Aplastic Anemia | Phase 2 | Not yet recruiting | Peking Union Medical College Hospital | 43 | 2026-04-01 | 2026-04-30 |
| A Study of Hetrombopag Combined With rhTPO in the Treatment of Cancer Therapy-induced Thrombocytopenia (CTIT) in Solid Tumor Patients. rhTPO + hetrombopag, hetrombopag - Cancer Therapy-induced Thrombocytopenia (CTIT) | Phase 2 | Not yet recruiting | Sun Yat-sen University | 204 | 2026-01-31 | 2026-01-12 |
| A Prospective, Multicenter Clinical Study of Hetrombopag in the Prevention of Thrombocytopenia Caused by Lung Cancer Therapy Hetrombopag Tablets - Lung Cancer | Phase 2 | Not yet recruiting | Shanghai Pulmonary Hospital, Shanghai, China | 149 | 2025-08-01 | 2025-08-03 |
| Dose-attenuated IST and Hetrombopag in Elderly (≥65 Years) Patients With Severe Aplastic Anemia Dose-attenuated IST and Hetrombopag - Sever Aplastic Anaemia, Elderly (People Aged 65 or More) | Phase 2 | Recruiting | Institute of Hematology & Blood Diseases Hospital, China | 65 | 2025-02-01 | 2025-06-08 |
| Efficacy and Safety of Hetrombopag in Preventing Chemotherapy-induced Thrombocytopenia in Gastrointestinal Tumors Hetrombopag - Chemotherapy-induced Thrombocytopenia (CIT) in Patients With Gastrointestinal Tumors | Phase 2 | Recruiting | Changhai Hospital | 40 | 2024-10-01 | 2026-03-25 |
| Observational Study: Hetrombopag for Platelet Recovery in Haploidentical HSCT Hetrombopag - Thalassemia in Children | Completed | Haikou Affiliated Hospital of Central South University Xiangya School of Medicine | 30 | 2024-09-01 | 2026-07-28 | |
| Hetrombopag in Promoting Platelet Engraftment After Auto-HSCT in Children With Neuroblastoma Hetrombopag - Delayed Platelet Engraftment, Neuroblastoma | Not applicable | Recruiting | Beijing Children's Hospital | 30 | 2024-06-30 | 2025-12-03 |
| TPO-RA Treatment on Immune Tolerance Induction of ITP Patients With Sustained Platelet Recovery After Treatment Termination Hetrombopag Olamine, Aspirin - Immune Thrombocytopenia | Phase 2 | Recruiting | Peking Union Medical College Hospital | 56 | 2024-06-20 | 2024-06-27 |
| Clinical Study on Efficacy and Safety of Hetrombopag in the Preoperative Patients of Thrombocytopenia Hetrombopag - Thrombocytopenia | Phase 4 | Unknown | The Third People's Hospital of Chengdu | 55 | 2024-06-01 | 2024-08-20 |
| The Efficacy and Safety of Hetrombopag as Secondary Prevention to Chemotherapy-induced Thrombocytopenia in Patients With Gynecologic Malignancies Hetrombopag - Chemotherapy-induced Thrombocytopenia | Phase 2 | Unknown | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 48 | 2023-10-16 | 2023-10-25 |
| The Efficacy and Safety of Hetrombopag in Primary Prevention of Thrombocytopenia Induced by the Niraparib Maintenance in Advanced Ovarian Cancer Patients Hetrombopag - Thrombocytopenia | Phase 2 | Unknown | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 34 | 2023-09-16 | 2023-09-14 |
| High-dose Dexamethasone Plus Hetrombopag vs High-dose Dexamethasone Alone as Frontline Treatment for Newly Diagnosed Adult Primary Immune Thrombocytopenia: A Prospective, Multicenter, Randomized Trial hetrombopag 5mg po qd, High-dose Dexamethasone - ITP - Immune Thrombocytopenia | Phase 2 | Unknown | Shandong University | 100 | 2023-09-15 | 2023-09-26 |
| Hetrombopag in Secondary Prevention of XPO-1 Inhibitor-induced Thrombocytopenia in Lymphoma Hetrombopag - Chemotherapy-Induced Thrombocytopenia | Phase 2 | Unknown | Sun Yat-sen University | 90 | 2023-09-04 | 2023-09-06 |
| Hetrombopag for the Treatment of Chemotherapy-Induced Thrombocytopenia in Adults With Solid Tumors. Hetrombopag, Hetrombopag plus Placebo, Placebo - Chemotherapy-Induced Thrombocytopenia | Phase 3 | Active not recruiting | Jiangsu HengRui Medicine Co., Ltd. | 213 | 2023-04-25 | 2025-04-16 |
| Hetrombopag for the Enhancement of Platelet Engraftment After Allogeneic Hematopoietic Stem Cell Transplantation Hetrombopag, placebo - Hematological Disease, Allogeneic Hematopoietic Stem Cell Transplantation | Not applicable | Unknown | Institute of Hematology & Blood Diseases Hospital, China | 78 | 2023-01-01 | 2023-02-14 |
| A Clinical Study of Hetrombopag Olamine Tablets for Thrombocytopenia Induced by Anti-tumor Treatment in Advanced Breast Cancer Hetrombopag - Breast Cancer | Phase 2 | Completed | Henan Cancer Hospital | 60 | 2022-09-21 | 2026-04-06 |
| Efficacy and Safety of Herombopag in Patients With Thrombocytopenia Before Hepatectomy Hetrombopag, Placebo - Hepatopathy | Phase 2 | Unknown | Fudan University | 96 | 2022-07-25 | 2024-03-13 |
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Purpura, Thrombocytopenic, Idiopathic (6) · Thrombocytopenia (5) · Anemia, Aplastic (3) · Breast Neoplasms (2) · Digestive System Diseases (1) · Hematologic Diseases (1) · Lung Neoplasms (1) · Myelodysplastic Syndromes (1) · Neuroblastoma (1) · Thalassemia (1)
Jiangsu HengRui Medicine Co., Ltd. (6) · Peking Union Medical College Hospital (4) · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University (3) · Fudan University (2) · Institute of Hematology & Blood Diseases Hospital, China (2) · Sun Yat-sen University (2) · Union Hospital, Tongji Medical College, Huazhong University of Science and Technology (2) · Beijing Children's Hospital (1) · Changhai Hospital (1) · Haikou Affiliated Hospital of Central South University Xiangya School of Medicine (1) · Henan Cancer Hospital (1) · Peking University People's Hospital (1) · Shandong University (1) · Shanghai Pulmonary Hospital, Shanghai, China (1) · The Third People's Hospital of Chengdu (1)
China (20)
Bing Han, Docter (1) · Bing Han, Master (1) · Erlie Jiang (1) · Heng Mei, PhD (1) · Huaiwu Lu (1) · Jia Wei, PhD (1) · Jing Li, Doctor (1) · Jun Shi, PhD (1) · Lu Wang, Professor (1) · Tienan Zhu, M.D. (1) · Xiaoyang Yang, MD (1) · Xueying Ding (1) · Zhiming Li, MD. (1)