3 completed, 1 recruiting. 4 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Completed 3, Recruiting 1 |
| Phase 2 | 4 | Completed 3, Recruiting 1 |
Follow Genetic Engineering: new trials by email Literature Review of Genetic Engineering trials Research Report on Genetic Engineering
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| HSV-tk + Valacyclovir + SBRT + Chemotherapy for Recurrent GBM ADV/HSV-tk (gene therapy) - Glioblastoma Multiforme, Astrocytoma, Grade III | Phase 1 / Phase 2 | Recruiting | David Baskin MD | 62 | 2017-12-11 | 2026-03-30 |
| Gene Therapy for X-linked Severe Combined Immunodeficiency Gene transfer - X-linked Severe Combined Immunodeficiency | Phase 1 / Phase 2 | Completed | Assistance Publique - Hôpitaux de Paris | 5 | 2010-12-01 | 2026-03-11 |
| Safety Study of Recombinant Adeno-Associated Virus Acid Alpha-Glucosidase to Treat Pompe Disease rAAV1-CMV-GAA (study agent) Administration, RMST - Pompe Disease | Phase 1 / Phase 2 | Completed | University of Florida | 9 | 2010-09-01 | 2018-09-14 |
| Gene Transfer for Severe Combined Immunodeficiency, X-linked (SCID-X1) Using a Self-inactivating (SIN) Gammaretroviral Vector Gene transfer - Severe Combined Immunodeficiency | Phase 1 / Phase 2 | Completed | David Williams | 8 | 2010-04-01 | 2026-04-21 |
X-Linked Combined Immunodeficiency Diseases (2) · Astrocytoma (1) · Glioblastoma (1) · Glycogen Storage Disease (1) · Glycogen Storage Disease Type II (1) · Infections (1) · Severe Combined Immunodeficiency (1)
Assistance Publique - Hôpitaux de Paris (1) · David Baskin MD (1) · David Williams (1) · University of Florida (1)
United States (3) · France (1)
Alain Fischer, MD, PhD (1) · Barry J Byrne, MD, PhD (1) · David S Baskin, MD (1) · Jennifer Whangbo, MD (1) · Shelley Collins, MD (1)
PMID 25295500, PMID 30261899, PMID 22794786, PMID 23570273
2008 (1), P01HL059412 (1)