6 completed, 2 terminated, 1 unknown. 6 Phase 2, 3 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Completed 5, Terminated 1 |
| Phase 3 | 3 | Completed 1, Terminated 1, Unknown 1 |
Follow fotemustine: new trials by email Literature Review of fotemustine trials Research Report on fotemustine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Treatment of Primary CNS Lymphoma ( FTD ) HD-MTX-Ara-C regimen, FTD regimen - Primary CNS Lymphoma (PCNSL) | Phase 2 | Completed | Mingzhi Zhang | 20 | 2017-03-02 | 2022-03-10 |
| Vemurafenib + Fotemustine to Treat Advanced Melanoma Patients With V600BRAF Mutation Recurred While on Vemurafenib Fotemustine + Vemurafenib - Malignant Melanoma Stage IV | Phase 2 | Completed | Paola Queirolo | 31 | 2013-02-01 | 2016-01-20 |
| A Study of Fotemustine(FTM) Vs FTM and Ipilimumab (IPI) or IPI and Nivolumab in Melanoma Brain Metastasis Fotemustine, Fotemustine and Ipilimumab, Ipilimumab and nivolumab - Brain Metastases | Phase 3 | Unknown | Italian Network for Tumor Biotherapy Foundation | 168 | 2012-12-01 | 2015-06-02 |
| A Study of Avastin (Bevacizumab) And Fotemustine in Patients With Recurrent Glioblastoma bevacizumab [Avastin], fotemustine - Glioblastoma Multiforme | Phase 2 | Completed | Hoffmann-La Roche | 91 | 2011-11-01 | 2016-03-15 |
| A Combination of Ipilimumab and Fotemustine for Treat Unresectable Locally Advanced or Metastatic Melanoma Ipilimumab and Fotemustine - Metastatic Malignant Melanoma | Phase 2 | Completed | Italian Network for Tumor Biotherapy | 86 | 2010-06-01 | 2015-05-13 |
| A Study of Avastin (Bevacizumab) in Combination With Fotemustine in Patients With Metastatic Melanoma bevacizumab [Avastin], fotemustine - Malignant Melanoma | Phase 2 | Completed | Hoffmann-La Roche | 20 | 2006-12-01 | 2018-12-06 |
| Intravenous or Hepatic Arterial Infusion of Fotemustine in Treating Patients With Unresectable Liver Metastases From Eye Melanoma fotemustine, isolated perfusion - Intraocular Melanoma, Metastatic Cancer | Phase 3 | Terminated | European Organisation for Research and Treatment of Cancer - EORTC | 171 | 2005-01-01 | 2012-09-24 |
| Fotemustine in Treating Patients With Metastatic Melanoma fotemustine - Melanoma (Skin) | Phase 2 | Terminated | Institut du Cancer de Montpellier - Val d'Aurelle | 12 | 2003-08-08 | 2025-02-14 |
| Fotemustine and Dacarbazine Versus Dacarbazine +/- Alpha Interferon in Advanced Malignant Melanoma Dacarbazine, Fotemustine, Interferon Alfa-2b - Malignant Melanoma, Recurrent Melanoma | Phase 3 | Completed | National Cancer Institute, Naples | 269 | 2002-04-01 | 2023-04-11 |
Melanoma (5) · Brain Neoplasms (1) · Glioblastoma (1) · Neoplasm Metastasis (1) · Uveal Melanoma (1)
Hoffmann-La Roche (2) · European Organisation for Research and Treatment of Cancer - EORTC (1) · Institut du Cancer de Montpellier - Val d'Aurelle (1) · Italian Network for Tumor Biotherapy (1) · Italian Network for Tumor Biotherapy Foundation (1) · Mingzhi Zhang (1) · National Cancer Institute, Naples (1) · Paola Queirolo (1)
Italy (6) · China (1) · France (1) · Poland (1) · Switzerland (1) · United Kingdom (1)
Anna Maria Di Giacomo, PhD,MD (1) · Antonio Daponte, M.D. (1) · Didier Cupissol, MD, PhD (1) · Michele Maio, MD, PhD (1) · Paola Queirolo, MD (1) · Paolo A Ascierto, M.D., Ph.D. (1) · Serge Leyvraz, MD (1) · Simona Signoriello, M.D. (1)
PMID 21030496, PMID 22027909, PMID 22894884, PMID 23402397, PMID 24510314, PMID 25538176, PMID 26951379, PMID 29552321
2004 (1)