Epothilones: Clinical Trials

6 trials of Epothilones, newest first

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4 completed, 2 active not recruiting. 6 Phase 2.

By phase and status

PhaseTrialsStatus
Phase 26Completed 4, Active not recruiting 2

Follow Epothilones: new trials by email Literature Review of Epothilones trials Research Report on Epothilones

Trials (filtered) newest first · largest first

All 6 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Ixabepilone in Treating Patients With Recurrent or Persistent Uterine Cancer
Ixabepilone, Laboratory Biomarker Analysis - Recurrent Uterine Corpus Sarcoma, Uterine Carcinosarcoma
Phase 2CompletedNational Cancer Institute (NCI)422010-09-072019-08-08
Paclitaxel, Carboplatin, and Bevacizumab or Paclitaxel, Carboplatin, and Temsirolimus or Ixabepilone, Carboplatin, and Bevacizumab in Treating Patients With Stage III, Stage IV, or Recurrent Endometrial Cancer
Bevacizumab, Carboplatin, Ixabepilone - Endometrial Adenocarcinoma, Endometrial Adenosquamous Carcinoma
Phase 2Active not recruitingNational Cancer Institute (NCI)3492009-09-142026-11-13
Ixabepilone in Treating Participants With Significant Residual Disease of HER2/Neu Negative Invasive Breast Cancer After Systemic Therapy
Best Practice, Ixabepilone - Bilateral Breast Carcinoma, HER2/Neu Negative
Phase 2Active not recruitingM.D. Anderson Cancer Center1162009-03-302026-11-10
A Phase II Combination of Trastuzumab and Ixabepilone Versus Trastuzumab and Docetaxel in Patients With Advanced and/or Metastatic Breast Cancer
ixabepilone, docetaxel, trastuzumab - Metastatic Breast Cancer
Phase 2CompletedR-Pharm502008-02-012016-03-10
Study to Assess Effectiveness of Giving Combination of Standard Chemotherapy Drugs Versus Combination of Standard Chemotherapy and New Drug Ixabepilone When Given Before Surgical Removal of Early Stage Breast Cancer
Ixabepilone, Paclitaxel, Cyclophosphamide - Breast Cancer
Phase 2CompletedBristol-Myers Squibb3842007-10-012016-02-24
A Phase II Study of Epothilone Analog BMS-247550 in Patients With Non-Small Cell Lung Cancer Who Have Failed First Line Platinum Based Chemotherapy
Epothilone - Carcinoma, Non-small-cell Lung
Phase 2CompletedR-Pharm2001-02-012016-02-10

Conditions studied

Breast Neoplasms (2)  ·  Carcinoma, Non-Small-Cell Lung (1)

Sponsors

National Cancer Institute (NCI) (2)  ·  R-Pharm (2)  ·  Bristol-Myers Squibb (1)  ·  M.D. Anderson Cancer Center (1)

Countries

United States (5)  ·  France (2)  ·  Italy (2)  ·  Spain (2)  ·  Argentina (1)  ·  Austria (1)  ·  Germany (1)  ·  Greece (1)  ·  India (1)  ·  Peru (1)  ·  Philippines (1)  ·  Russia (1)  ·  Singapore (1)  ·  South Korea (1)  ·  Taiwan (1)

Top investigators

Carol Aghajanian (1)  ·  Carolyn McCourt (1)  ·  Funda Meric-Bernstam (1)

Results publications

PMID 25913905, PMID 27312051, PMID 33541735, PMID 35658479

NIH funding

U10CA027469 (2), U10CA180868 (2)