6 completed, 2 terminated. 4 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Completed 3, Terminated 1 |
| Phase 2 | 4 | Completed 3, Terminated 1 |
Follow ELX-02: new trials by email Literature Review of ELX-02 trials Research Report on ELX-02
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of ELX-02 in Patients With Alport Syndrome ELX-02 - Alport Syndrome | Phase 2 | Completed | Eloxx Pharmaceuticals, Inc. | 3 | 2022-11-28 | 2026-02-24 |
| A Phase 2 Study to Evaluate the Safety, Tolerability, PK and PD of ELX-02 in Cystic Fibrosis Patients With G542X Allele ELX-02, Ivacaftor - Cystic Fibrosis | Phase 2 | Completed | Eloxx Pharmaceuticals, Inc. | 17 | 2019-11-25 | 2022-11-22 |
| A Phase 2 Study to Evaluate the Safety, Tolerability, PK and PD in Cystic Fibrosis Patients With at Least 1 G542X Allele ELX-02, Ivacaftor - Cystic Fibrosis | Phase 2 | Completed | Eloxx Pharmaceuticals, Inc. | 17 | 2019-11-05 | 2023-08-21 |
| A Phase 2 Study of ELX-02 in Patients With Nephropathic Cystinosis ELX-02 - Genetic Disease, Nonsense Mutation | Phase 2 | Terminated | Eloxx Pharmaceuticals, Inc. | 3 | 2019-08-02 | 2020-05-27 |
| A Study to Evaluate the Effects of Renal Impairment on the Pharmacokinetics of ELX-02 ELX-02 - Impaired Renal Function | Phase 1 | Completed | Eloxx Pharmaceuticals, Inc. | 24 | 2019-01-04 | 2021-04-13 |
| Phase 1 Study of ELX-02 in Healthy Adult Subjects ELX-02, Placebo - Genetic Disease, Nonsense Mutation | Phase 1 | Completed | Eloxx Pharmaceuticals, Inc. | 62 | 2017-10-11 | 2021-03-16 |
| Phase 1 Study of ELX-02 in Healthy Adults Placebo, ELX-02 - Genetic Disease, Nonsense Mutation | Phase 1 | Completed | Eloxx Pharmaceuticals, Inc. | 18 | 2017-09-26 | 2023-08-22 |
| Safety, Tolerability, Pharmacokinetics of ELX-02 in Healthy Adult Volunteers ELX-02, Placebo - Genetic Diseases, Nonsense Mutations | Phase 1 | Terminated | Eloxx Pharmaceuticals, Inc. | 42 | 2016-07-01 | 2019-10-22 |
Genetic Diseases, Inborn (4) · Cystic Fibrosis (2) · Cystinosis (1) · Nephritis, Hereditary (1) · Renal Insufficiency (1)
Eloxx Pharmaceuticals, Inc. (8)
Australia (2) · Belgium (2) · Canada (2) · United States (2) · Germany (1) · Israel (1) · United Kingdom (1)
Paul Goodyer, MD (1)